Mental Health–Ill Health Differences in Disease Severity and Its Sociodemographic Biobehavioral Predictors Among Patients With Knee Osteoarthritis

Abstract

Our aim in this cross-sectional study was to investigate mental health-ill health differences in disease severity and its sociodemographic biobehavioral predictors among patients with knee osteoarthritis (OA). Applying convenient sampling, 180 patients with knee OA in Tabriz, Iran, were recruited to participate in completing a three-section questionnaire (SF-12, Lequesne Algofunctional Index and Self-Management Behaviors Scale). Separate hierarchical multiple linear regressions were performed with OA severity as dependent variable: one for OA patients with positive mental health and other for OA patients with mental disorders symptoms. Among the patients with positive mental health, but not those with symptoms of mental disorder, pain management, duration of OA, physical activity management, living alone, and level of education were significant predictors of disease severity. Health care providers with a better understanding on the determinants of disease severity by mental health status may identify vulnerable patients and develop targeted interventions to foster disease management behaviors among OA patients.

Assessing the Burden of Osteoarthritis in Africa and the Middle East: A Rapid Evidence Assessment

“…In addition, 3 studies reported Lequesne Algofunctional Index of Disease Severity mean scores in patients with symptomatic/radiographic knee OA ( Table 4 ). 19 , 21 , 30 Among the population in Tunisia, Hana et al reported a mean severity score of 11, indicating very severe disability, and scores significantly higher in those ≥65 years of age compared with those <65 years of age. 21 In a Cameroon study, Bija et al found that the proportion of patients within higher score ranges increased with severity of radiographic grade of knee OA and 40% of patients with grade 4 symptomatic/radiographic knee OA had a score indicating extremely severe disability.…”

“…Comparisons with the other studies could not be made, however, because a different scoring scale was used. 30 …”

“…Of these, 20 publications reported studies from 10 countries in Africa and the Middle East (Figure 2). [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] Categorizing the studies by outcomes, 7 reported on epidemiology [15][16][17]19,24,25,28 (prevalence data only) and 16 reported on humanistic burden. [12][13][14][18][19][20][21][22][23][25][26][27][28][29][30][31] No studies reported on economic burden/outcomes, and no studies were identified that reported incidence, survival/death rates, or all-cause mortality rates.…”

“…[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] Categorizing the studies by outcomes, 7 reported on epidemiology [15][16][17]19,24,25,28 (prevalence data only) and 16 reported on humanistic burden. [12][13][14][18][19][20][21][22][23][25][26][27][28][29][30][31] No studies reported on economic burden/outcomes, and no studies were identified that reported incidence, survival/death rates, or all-cause mortality rates. All 20 publications were rated as satisfactory or higher quality for risk of bias (Online Resource 2) and all reported knee OA.…”

Causal Relationships Between Social Isolation and Osteoarthritis: A Mendelian Randomization Study in European Population

“… 1 , 11 , 12 Previous observational studies have already established the association between social isolation and osteoarthritis. 14 , 27 However, the traditional observational study designs are susceptible to interference from reverse causality and confounding factors, which limits the understanding of the relationship between social isolation and osteoarthritis. More importantly, different from general physical risk factors, the causal relationships between mental determinants and physical conditions are usually more complicated, which could be bidirectional.…”