Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging

Lacruz, María Elena; Emeny, Rebecca T.; Bickel, Horst; Cramer, B.; Kurz, Alexander; Bidlingmaier, Martin; Huber, Dorothea; Klug, Günther; Peters, Annette; Ladwig, Karl Heinz

doi:10.1186/1471-2288-10-36

Cited by 46 publications

(33 citation statements)

References 31 publications

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“…Resnick e Inquito la describen como la capacidad de alcanzar, mantener o recuperar un nivel de salud física o emocional después de la enfermedad o la pérdida (18), en donde el 82,4% fue clasificado con una alta capacidad, siguiéndole sólo un 17% de los adultos mayores, quienes fueron considerados con mediana resiliencia, por cuanto apunta a que los adultos mayores presentan una alta capacidad de afrontar los problemas, lo que conlleva a un "envejecimiento exitoso", concepto que ha sido popular durante muchas décadas (19). Sin embargo, al comparar este dato con otro informe publicado en 2008 luego de aplicar el GhQ-12 medidos en 3.581 participantes mayores de 50 años en el British household Panel Survey, se indicó una prevalencia de resiliencia del 14%.…”

Section: Discusión Y Conclusiónunclassified

Resiliencia Y Su Relación Con Estilos De Vida De Los Adultos Mayores Autovalentes

Recabal¹,

Leone²,

Muñoz

et al. 2012

Cienc. enferm.

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RESUMENObjetivo. Relacionar la capacidad de resiliencia de un grupo de adultos mayores autovalentes de la comuna de Chillán Viejo (Chile) respecto a sus estilos de vida. Material y métodos: Estudio de tipo correlacional y de corte transversal de 176 adultos mayores autovalentes de ambos sexos entre 65 y 85 años de edad asistentes a un centro de salud primaria de la comuna de Chillán Viejo Región del Bío-Bío, Chile. Se aplicó la escala Resiliencia de Wagnild y young adaptada por las autoras del estudio; empleándose la prueba de χ 2 o la prueba exacta de Fischer, cuando correspondiera, considerándose como significancia estadística p<0,05. Resultados. El 82,4% de los participantes del estudio poseen una alta capacidad de resiliencia. Se observó que la capacidad de resiliencia depende significativamente de la situación de pareja (p=0,002), la mantención de actividad sexual (p=0,008), las actividades recreativas (p=0,015) y el estado de ánimo (p=0,001). Conclusión. Existen características de sus estilos de vida que se relacionan en mayor medida a su nivel de resiliencia, que le permite enfrentar cambios propios del proceso natural de envejecimiento de los adultos mayores. Palabras clave:Resiliencia, adulto mayor, estilo de vida, actividades cotidianas. ABSTRACTObjective: Relate the resilience of a group of self-reliant elderly from Chillan Viejo County (Chile) with their life style. Design: Co relational and cross-sectional study of 176 self reliant both sexes elderly between 65 and 85 years old attending a primary health care unit at Chillán Viejo County, Bío-Bío Region, Chile. Wagnild and young Resilience Scale, adapted by the authors of this research, was applied using the χ 2 test or the Fishers exact test, when necessary, considering as statistically significant, p <0.05. Results: 82.4% of the subjects of study have a high resilience. It was observed that the resilience depends significantly on the condition of living with a partner (p=0.002), the capacity of sexual activity (p= 0.008), the recreational activities (p= 0.015) and the mood condition (p=0.001). Conclusion. There are characteristics in their life styles that relate themselves in a greater extent to their level of resilience which enables them to face changes that are typical of the natural process of aging among older adults.

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Section: Discusión Y Conclusiónunclassified

Resiliencia Y Su Relación Con Estilos De Vida De Los Adultos Mayores Autovalentes

Recabal¹,

Leone²,

Muñoz

et al. 2012

Cienc. enferm.

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“…One of the principal objectives of the KORA-Age study is to scrutinize potentially predictive factors of ‘successful aging' [32]. Hence, this study comprises numerous indicators for physical and mental health.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Use and Level of Awareness of CAM in Older People - Results from the KORA-Age Study

Weidenhammer

Lacruz²,

Emeny³

et al. 2014

Complement Med Res

Self Cite

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Background: Despite the growing proportion of older adults in Europe there is only limited knowledge of CAM use among the elderly. This analysis aims to provide estimates for the prevalence of CAM use in persons with an age of ≥65, and to investigate correlations of CAM use with demographic characteristics. Methods: Based on participants of the MONICA/KORA studies S1-S4 who were born before 1944, a random sample of 1,079 was selected for comprehensive medical examinations. Questions were presented in structured face-to-face interviews conducted from February to November 2009. Results: Data on CAM use were available for 1,026 subjects with a mean age of 76 years, ranging from 65 to 93 years. 14% of the participants were unaware of CAM. The overall prevalence of CAM use was estimated 37% with minor differences between age groups, but clear differences between male (29%) and female (44%) participants. 1-year prevalence of CAM use was 22% (16% males, 28% females). 1-year of CAM use was associated with a higher level of education in both men and women; with higher income in men; and with more actual diseases in women. Conclusion: Findings indicate that awareness of CAM is high even among people ≥65 years. Estimates for the prevalence of CAM use confirm the relevance of this treatment sector in the healthcare system for the elderly.

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“…The second category of quali es associated with successful ageing is considered as important as the first. They comprise several traits that are associated with personality characteris cs (ac ve engagement in life, sa sfac on with life, general op mis c mindset towards life); and one characteris c that is dependent on external factors -namely, one's spouse alive and (rela vely) healthy [1370][1371][1372][1373].…”

Section: S Snegov the Experiments Of Professor Bran Ng (1977)mentioning

confidence: 99%

DNA repair systems

Chakarov¹,

Petkova²,

Russev³

2014

Biodiscovery

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This paper provides detailed insight into the mechanisms of repair of different types of DNA damage and the direct molecular players (enzymes repairing the damage or tagging the damaged site for further processing; damage sensor molecules; other signalling and effector molecules). The gene c bases of diseases and condi ons associated with defec ve DNA repair are comprehensively reviewed, from the 'classic' severe diseases such as xeroderma pigmentosum and Cockayne syndrome to the much more subtle UV sensi vity syndromes. The review analyses the basic molecular mechanisms underlying the rela vely rare monogenic diseases of DNA repair and management of genome integrity as well as the common mul factorial diseases and condi ons with late onset that are associated with increased levels of oxida ve stress (metabolic syndrome, diabetes type 2, cardiovascular disease) and with accumula on of 'errors' in DNA (normal and pathological ageing phenotypes, various cancers). The role of cell cycle checkpoints in dividing cells and the mechanisms of decision-making for the fate of a damaged cell are discussed with regards to the cell homeostasis in normal and cancerous ssues. The role of major DNA damageassociated signalling and effector molecules (p53, ATM, poly-(ADP-ribose)-polymerase, DNA-dependent protein kinase, BRCA proteins, re noblastoma protein, and others) is discussed and illustrated with examples in the context of health and disease. DNA repair and programmed cell death are viewed together as a unified mechanism for limi ng the presence of damaged cells and cells with poten ally oncogenic transforma on in mul cellular organisms. Special a en on is paid to ageing as a natural phenomenon and an adap ve evolu onary mechanism, with a brief outline of 'successful ageing'. The differen al rates of repair of DNA in transcribed and nontranscribed regions of the genome and the specifici es of DNA repair profile in some types of cells (terminally differen ated cells, pluripotent stem cells, etc.) and in certain taxonomic groups (e.g. 'the rodent repairadox') are discussed with regards to replica ve ageing and the evolu onary processes on microand macroscale. The role of mutagenesis as a 'hit and miss' mechanism and the 'leakiness' of DNA repair for increasing gene c diversity in the course of individual life and on evolu onary scale and the phenomenology of ongoing molecular evolu on are extensively reviewed. Conflict of Interests:No poten al conflict of interest was disclosed by any of the authors. Types of DNA repair systemsIf you wish for peace, prepare for war.Publius Flavius Vege us Renatus, De Re Militari (circa 380 AD).DNA damage is a very broad term, encompassing many different types of lesions in DNA.Accordingly, DNA repair comprises many different types of pathways and mechanisms covering virtually every possible type of injury to the sequence or the structure of DNA.Accep ng Lewin's defini on of DNA damage "... any change that introduces a devia on from the usual double-helical structure" [1] , we may pre...

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Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging

Cited by 46 publications

References 31 publications

Resiliencia Y Su Relación Con Estilos De Vida De Los Adultos Mayores Autovalentes

Resiliencia Y Su Relación Con Estilos De Vida De Los Adultos Mayores Autovalentes

Prevalence of Use and Level of Awareness of CAM in Older People - Results from the KORA-Age Study

DNA repair systems

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