This study uses a stress process framework and person-centered methods to describe patterns of concurrent stressors across multiple domains and to associate patterns with female military spouse mental health. Background: Most military families are resilient. However, a subset of military spouses experiences adverse outcomes in the context of war-related stress. To date, a focus on military-specific stressors has largely obscured the effects of stress unrelated to military service on the well-being of military spouses. Methods: Data were drawn from a 2012 survey of 343 U.S. Army spouses, measuring intrapersonal (e.g., adverse childhood experiences), family (e.g., work-family conflict), and military stressors (e.g., cumulative deployments). Outcomes included moderate or more severe depression, anxiety, and posttraumatic stress disorder (PTSD). Results: The three-step method of latent class analysis identified three classes: low (58.86% of participants), moderate (21.62%), and high (19.52%) stress. Prevalence of mental health problems was significantly elevated in the high-stress class. In this group, 35.3%, 36.3%, and 39.5% of spouses' screenings indicated at least moderate depression, anxiety, and PTSD symptomatology, compared with 3.0%, 3.9%, and 2.7% in the low-stress group. Conclusions: Results suggest many military spouses have low stress exposure across domains and low rates of mental health symptoms. However, a subset of spouses may experience both intrapersonal and family-level risk associated with elevated rates of mental health problems. Implications: Findings highlight the critical role of nonmilitary stressors in the lives of military spouses and the