Mental Health Status and Quality of Life in Undiagnosed Glaucoma Patients

Jung, Kyoung In; Park, Chan Kee

doi:10.1097/md.0000000000003523

Cited by 34 publications

(35 citation statements)

References 41 publications

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“…The analyses show that visual impairment caused by glaucoma affects the life quality of the patients, especially with less educated individuals [22,23,24]. The main goals of the glaucoma treatments are to preserve the visual functions of patients and to preserve/increase their life quality [25,26,27].…”

Section: Discussionmentioning

confidence: 99%

Hospitalization characteristics of patients with glaucoma in Central and West Serbia

et al. 2019

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Introduction/Objective Glaucoma is a chronic disease that impairs the optic nerve irreversibly and can lead to serious loss of vision and blindness. As the most frequent out of all, primary open-angle glaucoma has a worldwide incidence of 2.4 million. The objective of this article is to examine the characteristics of glaucoma hospitalization patterns in Central and West Serbia in the 2006-2017 period. Methods This study was a retrospective analysis of glaucoma hospitalizations in the Kragujevac Clinical Center from 2006 to 2017 (n = 1,751). All hospitalizations were divided according to discharge diagnoses into the following three subgroups: primary open-angle glaucoma, the primary closure glaucoma, and secondary glaucoma and other glaucoma types. Results The average hospitalization rate for glaucoma is 5/10,000 inhabitants. The lowest rate was recorded in 2013 (1.8/10,000) and the highest in 2015 (9.3/10,000). The rehospitalization rate ranged from 0.5/10,000 in 2013 to 6.9/10,000 in 2015, with an average of 2.4 patients per 10,000. The most common glaucoma was secondary glaucoma and other glaucoma types (44.6%), followed by primary open-angle glaucoma (37.9%) and primary closure glaucoma (17.5%). The average hospitalization length was 6.5 ± 4.9 days and it decreased from the average 9.7 ± 6.5 (2006) to 5.5 ± 3.7 days (2013) (p < 0.01) in all glaucoma types. Conclusion There was a significant reduction of the hospitalization length in all glaucoma types in Central and West Serbia. The hospitalization rates varied with a significant increase since 2013, which is the consequence of the increase in rehospitalization rates.

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Section: Discussionmentioning

confidence: 99%

Hospitalization characteristics of patients with glaucoma in Central and West Serbia

et al. 2019

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“…However, the diagnosis of glaucoma was based on self-report, even though a strength of that study was that it was a large prospective study [ 14 ]. This could result in a selection bias because over half of individuals with glaucoma are not aware of their condition [ 21 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Dietary Niacin and Open-Angle Glaucoma: The Korean National Health and Nutrition Examination Survey

2018

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Glaucoma is a leading cause of loss of sight. High intraocular pressure (IOP) is the most critical risk factor. However, glaucoma develops even within a normal IOP range. Normal tension glaucoma (NTG) is more common in Asia, whereas high tension glaucoma is more common in Western countries. The pathogenesis of glaucoma, especially NTG, is poorly understood. We evaluated the correlation between dietary nutrient intake and glaucoma using data from subjects ≥40 years old from the ongoing, nationwide, population-based study, the Korean National Health and Nutrition Examination Survey V (2008–2012). Dietary intake was determined using the 24 h recall method. Fiber (g/day), ash (g/day), calcium (mg/day), phosphorus (mg/day), iron (mg/day), sodium (mg/day), potassium (mg/day), β-Carotene (μg/day), retinol (μg/day), vitamin A (μg Retinol Equivalents/day), thiamine (mg/day), riboflavin (mg/day), niacin (mg/day), and vitamin C (mg/day) were included in nutrient intake data. All nutrient intake was divided into quartiles. The mean IOP did not differ according to quartiles from any nutrients (all p > 0.05). After adjusting for age, gender, income status, education level, smoking, alcohol consumption, physical activity, diabetes, hypertension, IOP, and total energy, the intake of niacin was associated with glaucoma (p = 0.013). Among subjects with IOP ≤ 21 mmHg, only niacin was related to glaucoma in a multivariate analysis (p = 0.022). Dietary nutrient intake was associated with open-angle glaucoma independent of IOP. Individuals with NTG showed lower intake of niacin among nutrients. This finding suggests the possibility that proper diet counseling may be another modifiable factor, aside from IOP, particularly among patients with NTG.

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“…We previously reported that subjects with undiagnosed glaucoma were more depressed than those without glaucoma in a population-based study [ 7 ]. Without considering the perception of the disease or the side defects of treatment, glaucoma patients still seem to have a higher possibility of presenting with depressive symptoms.…”

Section: Introductionmentioning

confidence: 99%

Attenuated Visual Function in Patients with Major Depressive Disorder

Jung

Hong

Shin

et al. 2020

JCM

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Background: We sought to investigate visual function, primarily, and structural changes in retinal ganglion cells, secondarily, in patients with major depressive disorder. Methods: A total of 50 normal participants and 49 patients with major depressive disorder were included in this cross-sectional study. The participants underwent 24–2 standard automated perimetry and spectral-domain optical coherence tomography. Results: The pattern standard deviation (PSD) in the visual field test was higher in the major depressive disorder patients than in the normal control subjects (p = 0.017). The patients with major depressive disorder showed reduced minimum ganglion cell–inner plexiform layer (GCIPL) thickness relative to the normal control participants (p = 0.015). The average score on the Hamilton Depression Rating scale showed a significant correlation with the PSD, minimum GCIPL thickness, and inferior GCIPL thickness (r = 0.265, p = 0.009; r = −0.239, p = 0.017; and r = −0.204, p = 0.043, respectively). The multivariate analysis of factors associated with PSD showed old age and a high Hamilton Depression Rating score to be relevant (p = 0.002 and 0.028, respectively). Conclusions: Visual function was decreased and the GCIPL thickness was reduced in major depressive disorder patients. The retinal neurodegenerative process in depression might be considered in patients with depression.

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Mental Health Status and Quality of Life in Undiagnosed Glaucoma Patients

Cited by 34 publications

References 41 publications

Hospitalization characteristics of patients with glaucoma in Central and West Serbia

Hospitalization characteristics of patients with glaucoma in Central and West Serbia

Dietary Niacin and Open-Angle Glaucoma: The Korean National Health and Nutrition Examination Survey

Attenuated Visual Function in Patients with Major Depressive Disorder

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