The objective was to examine cognitive correlates of mental pain (MP) experiences in adult survivors of pediatric cancer in terms of meaning assignment tendencies. The hypotheses were that MP in the present and in the past would correspond to a pattern of meaning variables reflecting the subjects approach to MP.The objective was to examine cognitive correlates of mental pain experiences in adult survivors of pediatric cancer. The specific correlates on which the study focuses are meaning assignment tendencies, such as tendencies to focus on functions of objects or emotional manifestations or temporal and locational characteristics that mediate the manner in which an individual perceives and conceptualizes the world around or within him or her. Previous studies were devoted to identifying the sets of meaning assignment tendencies corresponding to constructs such as personality traits or specific emotions [1][2][3][4][5]. Sets of meaning assignment tendencies provide insights into the nature and functioning of the studied construct and enable planning guidelines for improved coping.The number of patients who survive pediatric cancer is about 80% and is increasing [6]. This situation has prompted an expanding effort to examine the late effects of pediatric cancer and its treatments so as to devise improved methods for helping the patients and their families. The medical problems of pediatric cancer survivors are common and have been the theme of many studies [7]. The psychological problems of pediatric cancer survivors are likely to be no less frequent in view of the duration, the difficulties, the pain and the anxiety often involved in undergoing the procedures of diagnosis, testing and treatments for pediatric cancer [8,9]. Studies show that in comparison to healthy subjects pediatric cancer survivors have a lower QOL [10], poor self-esteem and academic difficulties [11]. lower self-concept [12], more depression, anxiety, pain, and insomnia [13], fatigue, emotional symptoms Method: The sample included 61 adult childhood cancer survivors (mean age was 25.03 years (SD = 5.56) ranging from 18 to 41 years), who had been diagnosed and treated, mostly (n = 27) for lymphoma, M = 12.84 years ago, at the age of M = 12.2 years. The tools were: A background information questionnaire; The MP questionnaire (Orbach) and the Test of Meanings (Kreitler).Results: A two-step factor analysis of the meaning variables yielded eight meaning-based factors shared by MP in the present and in the past. Regression analyses with age, gender and marital status in the first step and the eight meaning-based predictors in the second step provided significant results showing that MP in the past was related to more predictors than MP in the present and focused mainly on shifting away through avoidance and negation from the painful themes this preventing coping with them productively. The results provide guidelines for coping interventions.