Mental Retardation and Developmental Disabilities Influenced by Environmental Neurotoxic Insults

Schroeder, Stephen R.

doi:10.2307/3454526

Cited by 4 publications

(4 citation statements)

References 6 publications

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“…These disabilities include disorders of learning, attention, emotional state and behavior. Mental retardation impacts two percent of children, or approximately 1.4 million children (9)(10)(11)(12). ADHD is conservatively estimated to occur in three to six percent, or approximately two million children (13) (14).…”

Section: Incidencementioning

confidence: 99%

Scientific & review committee

2017

2017 28th Irish Signals and Systems Conference (ISSC)

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Section: Incidencementioning

confidence: 99%

Scientific & review committee

2017

2017 28th Irish Signals and Systems Conference (ISSC)

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“…stressful life events). Numerous factors acting during early development of a foetus may contribute to the genesis of a neurodevelopmental disorder, including insufficient maternal nutrition, daily smoking, viral infection and repeated psychological stress [ 182 ]. Most environmental vulnerability factors are however difficult to assign and quantify.…”

Section: Complex Neurodevelopmental Disorders and The Environmentmentioning

confidence: 99%

Genetic and Environmental Factors in Complex Neurodevelopmental Disorders

Loo¹,

Martens

2007

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Abstract:Complex neurodevelopmental disorders, such as schizophrenia, autism, attention deficit (hyperactivity) disorder, (manic) depressive illness and addiction, are thought to result from an interaction between genetic and environmental factors. Association studies on candidate genes and genome-wide linkage analyses have identified many susceptibility chromosomal regions and genes, but considerable efforts to replicate association have been surprisingly often disappointing. Here, we summarize the current knowledge of the genetic contribution to complex neurodevelopmental disorders, focusing on the findings from association and linkage studies. Furthermore, the contribution of the interaction of the genetic with environmental and epigenetic factors to the aetiology of complex neurodevelopmental disorders as well as suggestions for future research are discussed.

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“…Neurotoxicants also target developmental processes, including cell replication, cell differentiation, and neural communication (Porterfield, 2000; Rice & Barone, 2000; Rodier, 1995). Because normal neurologic development is based on exquisitely choreographed sequences of cellular events, such chemical disruption has been related to disabilities, including mental retardation (Myers & Davidson, 2000; Schroeder, 2000), cerebral palsy, epilepsy, and deficits of learning, memory, and attention (Myers & Davidson, 2000; Porterfield, 2000), attention-deficit/hyperactivity disorder (Rice, 2000), and possibly even autism (London & Etzel, 2000).…”

Section: Environmental Toxicantsmentioning

confidence: 99%

Environmental Toxicants and Developmental Disabilities: A Challenge for Psychologists.

Koger¹,

Schettler²,

Weiss³

2005

American Psychologist

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Developmental, learning, and behavioral disabilities are a significant public health problem. Environmental chemicals can interfere with brain development during critical periods, thereby impacting sensory, motor, and cognitive function. Because regulation in the United States is based on limited testing protocols and essentially requires proof of harm rather than proof of lack of harm, some undefined fraction of these disabilities may reflect adverse impacts of this "vast toxicological experiment" (H. L. Needleman, as quoted in B. Weiss & P. J. Landrigan, 2000, p. 373). Yet the hazards of environmental pollutants are inherently preventable. Psychologists can help prevent developmental disabilities by mobilizing and affecting public policy, educating and informing consumers, contributing to interdisciplinary research efforts, and taking action within their own homes and communities to reduce the toxic threat to children.

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Mental Retardation and Developmental Disabilities Influenced by Environmental Neurotoxic Insults

Cited by 4 publications

References 6 publications

Scientific & review committee

Scientific & review committee

Genetic and Environmental Factors in Complex Neurodevelopmental Disorders

Environmental Toxicants and Developmental Disabilities: A Challenge for Psychologists.

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