Mepivacaine for Spinal Anesthesia in Parturients Undergoing Elective Cesarean Delivery: Maternal and Neonatal Plasma Concentrations and Neonatal Outcome

Abstract

Particularly with short duration of surgery (21 +/- 5 min) intrathecal mepivacaine combined with fentanyl offers a favorable clinical alternative in parturients undergoing elective Cesarean delivery.

Mepivacaine Versus Bupivacaine in Adult Surgical Patients: A Meta-analysis, Trial Sequential Analysis of Randomized Controlled Trials

“…12 Recent data on modern formulations of mepivacaine have since demonstrated that TNS incidence is consistent with bupivacaine and other intrathecal local anesthetics. 13 Several studies have investigated mepivacaine for a variety of surgeries, including axillary brachial plexus block in the minor orthopedic forearm, wrist or hand surgery, 14 spinal anesthesia after elective Cesarean delivery, 15 knee arthroscopy surgery, 16 and lateral popliteal nerve blockade in foot and ankle surgery. 17 There was no systematic review comparing the anesthetic effects of mepivacaine with bupivacaine in adult surgical patients.…”