Abstract::
In recent times, technological and scientific advances have been made in studying and
developing orally delivered medication. Such studies demonstrate the importance of the oral route
among patients. The accuracy of drug delivery is very important to achieve a successful therapeutic
effect in the case of various pharmaceutical products. A novel drug delivery system adds new benefits
or advantages to a drug. This review covers all the aspects of medicated chewing gum (MCG)
as a new drug delivery method, including the benefits and drawbacks, manufacturing methods, type
of MCG, composition of chewing gum, evaluation parameters, factors that affected the release of
API, its pharmaceutical significance, various marketed chewing gum and chewing gum packaging.
Chewing gum as a drug delivery system has the potential to cure or prevent various indications,
such as analgesic, CNS stimulation, smoking cessation, motion sickness, and treatment and prevention
of dental caries or gingivitis. Pharmaceutical distribution to the oral mucosa can be made more
convenient and enticing with the help of MCG. Compared to conventional techniques, this delivery
system has a longer-lasting effect, which makes it a viable option for treating digestive problems,
headaches, migraines, coughing, anxiety, and allergies.