“…Essential elements such as nickel (Ni), manganese (Mn), copper (Cu), chromium (Cr), iron (Fe) and zinc (Zn) are required in a specific amount for normal function of living beings, while their higher concentration could induce harmful effects [11,12]. Toxic elements include lead (Pb), cadmium (Cd), arsenic (As) and mercury (Hg) are hazardous for living beings even in minute concentration [13,14]. The harmful effects of these PTE are headache, abdominal pain, vomiting, irritability, hypertension, nausea, kidney, liver and intellectual problems, mental retardation, anemia, nerve damages and problem, heart problem, teratogenesis and carcinogenesis [15].…”