Merino wool graduated compression stocking increases lower limb venous blood flow: A randomized controlled trial

Charles, T.; Mackintosh, Deborah; Healy, Bridget; Perrin, Kyle; Weatherall, Mark; Beasley, Richard

doi:10.1007/s12325-010-0107-5

Cited by 22 publications

(22 citation statements)

References 27 publications

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“…Moreover, patients should avoid any superimposed transient provoking factors of VTE. If any -more aggressive form of prophylaxis should be considered, taking into account also physical methods such as elastic prevention stocking [76,77]. In patients at JAK2-related high risk of VTE low-dose aspirin is highly recommended -as its efficacy has been demonstrated in ECLAP study [58] and tent to decrease VTE occurrence also according to the results of our study.…”

Section: Discussionmentioning

confidence: 62%

The JAK2 V617F mutational status and allele burden may be related with the risk of venous thromboembolic events in patients with Philadelphia-negative myeloproliferative neoplasms

Borowczyk

Wojtaszewska

Lewandowski

et al. 2015

Thrombosis Research

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Section: Discussionmentioning

confidence: 62%

The JAK2 V617F mutational status and allele burden may be related with the risk of venous thromboembolic events in patients with Philadelphia-negative myeloproliferative neoplasms

Borowczyk

Wojtaszewska

Lewandowski

et al. 2015

Thrombosis Research

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“…The apparent lack of a significant change from baseline in measures of popliteal vein blood flow or vein diameter with the GCS intervention does not necessarily indicate a lack of physiological effect, as blood flow progressively decreases and vein diameter increases over time with sitting [20]. It is probable that the GCS prevented these physiological changes that would have occurred in the model of venous stasis secondary to prolonged seated immobility.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Micromobile Foot Compression Device in Increasing Lower Limb Venous Blood Flow

Charles

Mackintosh

Fingleton

et al. 2013

International Journal of Vascular Medicine

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Background. A novel, micromobile foot compression device (MMC) has been developed to reduce the risk of venous thromboembolism associated with prolonged seated immobility. Objective. To compare the efficacy of the MMC with graduated compression stockings in augmenting lower limb venous blood flow. Patients/Methods. Twenty participants were randomised to wear the MMC or a graduated compression stocking (GCS) on either the left or right leg while seated. Doppler ultrasound measurements of popliteal vein blood flow and leg circumference measurements were made −30 and −10 minutes (baseline) and +30 and +60 minutes following application of the interventions. The primary outcome variable was peak systolic velocity. A mixed linear model was used, with covariates including baseline measurement, randomised side, time, and a time by interaction term. Results. The mean popliteal vein peak systolic velocity at 60 minutes with the MMC was 20.1 cm/s which was significantly higher than with the GCS (difference 14.1 cm/s 95% CI 12.1–16.2), representing a 3.8-fold increase from baseline. Conclusion. The MMC resulted in a marked increase in lower limb venous blood flow which suggests that it may have efficacy in reducing the risk of venous thromboembolism associated with prolonged seated immobility, such as long distance air travel.

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“…[1][2][3][4][5][6][7] Pharmacological prophylaxis carries the risk of severe bleeding, and in patients who are at the risk of bleeding, such as those with cancer or postspinal surgery, mechanical prophylaxis must be used. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] One recommended method of mechanical VTE prophylaxis is active leg movement. 7,8,11,12 Combined ankle movement improves venous velocity in the lower extremities more effectively than single ankle movement.…”

Section: Introductionmentioning

confidence: 99%

A novel exercise device for venous thromboembolism prophylaxis improves venous flow in bed versus ankle movement exercises in healthy volunteers

Shimizu

Kamada

Sakane

et al. 2017

J Orthop Surg (Hong Kong)

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Purpose: Venous thromboembolism prophylaxis is crucial. To facilitate active ankle movement in postoperative and bedridden patients, we developed a novel leg exercise apparatus (LEX). We investigated the effect of the LEX by comparing increases in lower extremity venous flow during different modes of exercise using the LEX. Methods: In eight healthy participants, we measured venous flow volume and velocity in the femoral vein using duplex ultrasonography at 1, 10, 20, and 30 min after completing three modes of 1-min LEX exercises. The exercises involved (1) rapid single motion (ankle dorsi-plantar flexion; 60 cycles/min); (2) slow single motion (30 cycles/min); and (3) slow combined leg motion. Results: Flow volumes after modes 1, 2, and 3 were 1.63-, 1.39-, and 1.53-fold above baseline at 30 min, respectively. Short periods of rapid single motion, with the LEX, improved postexercise lower extremity venous flow volumes at 30 min and mean venous flow velocity at 20 min, compared to slow single motion exercise. Even at slow speeds, combinedmotion improved flow volume compared to single motion. Conclusion: Short periods of rapid single motion exercise, with the LEX, improved postexercise venous flow volumes in the lower extremities at 30 min and mean venous flow velocity at 20 min. These effects were greater than those produced by slow single motion exercises. However, even at slow speeds, combined-motion exercises improved flow volume compared to single motion. Therefore, LEX may prove effective at preventing thromboembolism in postoperative and bedridden patients.

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Merino wool graduated compression stocking increases lower limb venous blood flow: A randomized controlled trial

Cited by 22 publications

References 27 publications

The JAK2 V617F mutational status and allele burden may be related with the risk of venous thromboembolic events in patients with Philadelphia-negative myeloproliferative neoplasms

The JAK2 V617F mutational status and allele burden may be related with the risk of venous thromboembolic events in patients with Philadelphia-negative myeloproliferative neoplasms

Efficacy of Micromobile Foot Compression Device in Increasing Lower Limb Venous Blood Flow

A novel exercise device for venous thromboembolism prophylaxis improves venous flow in bed versus ankle movement exercises in healthy volunteers

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