Meriones unguiculatus as an experimental host for Taenia saginata metacestodes

Wouters, Guido; Geerts, S.; Brandt, J.; Kumar, V.; Calus, A.

doi:10.1016/0020-7519(88)90048-3

Cited by 3 publications

(3 citation statements)

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“…They cannot be attributed with certainty to T. saginata. Meriones unguiculatus (by injection: [101]) and sheep (oral route: [44]) did not prove very effective; however the influence of sewage sludge fertilisation on pastures grazed by rodents and small ruminants remains unclear and requires further investigation.…”

Section: The Intermediary Hosts Of T Saginatamentioning

confidence: 98%

The use of urban sewage sludge on pastures: the cysticercosis threat

Cabaret¹,

Geerts

Madeline³

et al. 2002

Vet. Res.

112

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-Urban sewage production is increasing and its agronomical use as a fertiliser has been advocated. Considerable defiance is prevalent in consumers and among farmers on the use of such fertilisers due to unknown pathological or environmental risks. The aim of the present review was to consider which pathological risk is major. Cysticercosis due to Taenia saginata appears to be one of the major pathological threats when sewage sludge is used to fertilise cattle pastures in temperate areas. The situation is different in Africa (Taenia solium and T. saginata are both highly prevalent) and Asia (Taenia saginata-like are prevalent). The processing of sludge and the delay between its application onto a pasture and grazing are probably major risk factors. Little data are available on the influence of processing, delay between processing and the use of sludge on the pathogenic risk. Producers and consumers will be more confident on the use of sludge if objective data are gained on risk. Most of the cases of cysticercosis (North America, United-Kingdom, Germany or Denmark) are related to poor human hygiene or accidental overflooding of sewage plants onto pastures. The standard application of sludge on pastures is apparently at low risk. This low risk does not mean that surveillance should cease since outbreaks of cysticercosis have been reported. Future investigations should concentrate on the most sustainable means of reducing risk (length of storage before use, composting, other treatments).urban sludge / parasite / cysticercosis / cattle / human Résumé -L'utilisation des boues d'épuration urbaine sur les pâturages : le risque de cysticercose. La production de boues urbaines résiduaires est en augmentation. Leur emploi agronomique comme fertilisant a été proposé. Une méfiance profonde des consommateurs ou des exploitants agricoles quant à l'emploi des boues urbaines en tant que fertilisants est réelle, qu'il s'agisse de risque pathologique ou environnemental. Le but de cette synthèse est de déterminer quel est le risque pathologique majeur. L'infestation par Taenia saginata semble être le risque le plus important en relation avec l'application 575 Vet. Res. 33 (2002) (33) 2 47427774; e-mail: cabaret@tours.inra.fr de boues d'épandages sur les pâturages bovins dans les régions tempérées. La situation est différente en Afrique (Taenia solium et T. saginata sont tous les deux très prévalents) et en Asie (les Taenia ressemblant à T. saginata ont un spectre d'hôtes herbivores assez large). Les processus de fabrication des boues et le délai entre le dépôt sur pâture et l'accès à la pâture sont sans doute des facteurs essentiels du risque. De rares données sont disponibles quant au délai et au traitement pour ce qui concerne leur pouvoir pathogène. Elles devraient être développées afin d'améliorer la confiance entre producteurs et consommateurs, sur des bases objectives. Le risque lié à l'épandage est faible comme le montrent des études aux USA, en Grande-Bretagne, Allemagne ou Danemark. La principale cause de risqu...

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Section: The Intermediary Hosts Of T Saginatamentioning

confidence: 98%

The use of urban sewage sludge on pastures: the cysticercosis threat

Cabaret¹,

Geerts

Madeline³

et al. 2002

Vet. Res.

112

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“…Mongolian gerbils have been used as a rodent models for the development of human taeniids. Geerts et al (1981Geerts et al ( /1982 and Wouters et al (1988) reported that the metacestode of T. saginata could be recovered from Mongolian gerbils which were subcutaneously inoculated with hatched oncospheres but not from gerbils intraperitoneally inoculated. Although we did not inoculate the hatched oncopheres of T. asiatica intraperitoneally into gerbils, the present result concurred with the finding that metacestodes could be recovered from gerbils subcutaneously inoculated with hatched oncospheres.…”

Section: Discussionmentioning

confidence: 99%

“…Compared to SCID mice, Mongolian gerbils do not require any special facility, and they have been used as animal model for many parasites. For human Taenia species, only T. saginata metacestodes (Belgian isolate and African isolate) had been reported to develop in gerbils subcutaneously inoculated with hatched oncospheres (Geerts et al, 1981(Geerts et al, /1982Wouters et al, 1988), and no study has been done with T. asiatica. Thus, in the first part of this study, Mongolian gerbils were orally inoculated with eggs or subcutaneously injected with hatched oncospheres to examine whether the animal can serve as an alternative intermediate host.…”

Section: Introductionmentioning

confidence: 99%

Development of Taenia asiatica cysticerci to infective stage and adult stage in Mongolian gerbils

et al. 2006

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The development of metacestodes and adult worms of Taenia asiatica in Mongolian gerbils (Meriones unguiculatus) were observed. Cysticerci were recovered from gerbils subcutaneously injected with hatched oncospheres. The recovery rate ranged from 0.1 to 3.2%. No cysticerci were recovered from the orally inoculated gerbils. The infectivity of the cysticerci recovered at 48 weeks post-infection was evaluated. Tapeworms were recovered on day 14 postinfection from the small intestine of 5 of 11 gerbils, with a recovery rate of 27% (6 worms recovered/22 worms inoculated). Three and four adult worms were recovered from two human volunteers who ingested five cysticerci after 4 months post-infection. In worms recovered from gerbils, segmentation and genital primordia in the posterior proglottids and hooklets in the residual rostellum were observed. The results indicate that gerbils can serve as an alternative intermediate host and that partial development of the adult worm stage occurs in gerbils.

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Human Taenia in Severe Combined Immunodeficiency (SCID) Mice

Itō

Ito

1999

Parasitology Today

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Meriones unguiculatus as an experimental host for Taenia saginata metacestodes

Cited by 3 publications

References 5 publications

The use of urban sewage sludge on pastures: the cysticercosis threat

The use of urban sewage sludge on pastures: the cysticercosis threat

Development of Taenia asiatica cysticerci to infective stage and adult stage in Mongolian gerbils

Human Taenia in Severe Combined Immunodeficiency (SCID) Mice

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