2024
DOI: 10.3390/ijms25105109
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MerTK Drives Proliferation and Metastatic Potential in Triple-Negative Breast Cancer

Mari Iida,
Bridget E. Crossman,
Kourtney L. Kostecki
et al.

Abstract: Triple-negative breast cancer (TNBC) is characterized by the absence of the estrogen receptor, progesterone receptor, and receptor tyrosine kinase HER2 expression. Due to the limited number of FDA-approved targeted therapies for TNBC, there is an ongoing need to understand the molecular underpinnings of TNBC for the development of novel combinatorial treatment strategies. This study evaluated the role of the MerTK receptor tyrosine kinase on proliferation and invasion/metastatic potential in TNBC. Immunohistoc… Show more

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