Mesenchymal hamartoma of the liver: a case report

Alwaidh, M. H.; Woodhall, Cynthia R.; Carty, Helen

doi:10.1007/s002470050113

Cited by 45 publications

(37 citation statements)

References 2 publications

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“…We retrospectively reviewed the ultrasound of our case and confirmed that the fetal liver was normal until 29 weeks of gestation. This observation that the placental lesion precedes the development of hepatic mesenchymal hamartoma is similar to another case report [15]. The most striking feature is the similarity of the edematous, myxoid changes in both the placenta and liver.…”

Section: Discussionsupporting

confidence: 74%

Hepatic Mesenchymal Hamartoma Associated with Mesenchymal Stem Villous Hyperplasia of the Placenta

Ruchelli¹,

Weiner²,

Ns³

2000

Fetal Diagn Ther

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A rare case of prenatally diagnosed hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta is presented and the literature reviewed. The placenta was noticed to have multiple cysts at 16 weeks’ gestation and elevated maternal serum α-fetoprotein was present. Cystic liver masses were first detected in the fetus at 34 weeks’ gestation. The liver mass showed a progressive enlargement during the third trimester and after birth, necessitating extended left hepatic trisegmentectomy at 3 months of age. Histological examination established the diagnosis of mesenchymal hamartoma of the liver and mesenchymal stem villous hyperplasia of the placenta. This is the first report of this association in which both lesions were diagnosed in utero and confirmed by histology after delivery. The likely pathogenesis of these strikingly similar lesions is discussed.

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Section: Discussionsupporting

confidence: 74%

Hepatic Mesenchymal Hamartoma Associated with Mesenchymal Stem Villous Hyperplasia of the Placenta

Ruchelli¹,

Weiner²,

Ns³

2000

Fetal Diagn Ther

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show abstract

“…In spite of only a few reports of MSVHP and about 40 reports of neonatal HMH in the literature, there have been already described 2 newborn patients with the association of neonatal HMH and MSVHP [5,6]. Only the patient reported by Kitano et al [5] had a prenatal US detection of both hepatic and placental mesenchymal lesions as we describe in the present report.…”

Section: Discussioncontrasting

confidence: 57%

Congenital hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta: case report

Carta

Maresi

Giuffrè

et al. 2005

Journal of Pediatric Surgery

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“…In 2 of these, there was placental vascular thrombosis or bleeding, probably because of umbilical vein obstruction by the fetal tumor: 1 fetus was stillborn [17] and the other was hydropic [26]. In 3 other cases, MHL was associated with mesenchymal stem villous hyperplasia of the placenta [27,28,64]; maternal serum aFP was elevated in 2, but in only 1 was the liver tumor detected prenatally [28]. In another fetal MHL, transient multicystic enlargement of the placenta was noted in midgestation [23].…”

Section: Prenatal Diagnosis and Outcomementioning

confidence: 94%

“…Magnetic resonance angiography is particularly useful when planning resection. Radioisotope scanning with technetium usually shows photopenic areas in the liver corresponding to larger cysts [55,60]; biliary excretion scans do not show evidence of a communication between cysts and the biliary tree [64].…”

Section: Investigationsmentioning

confidence: 99%