Mesenchymal Stem Cells: Innovative Therapeutic Intervention for Autoimmune Rheumatic Diseases

Abstract

Mesenchymal stem cells (MSCs) are multi-potential non-hematopoietic progenitor cells capable of immuno-modulatory activities that diminish adaptive and innate immune responses. MSCs have been the object of multiple publications because their ability to regulate the immunological system and converted MSCs into a promise of developing cell therapies for various autoimmune rheumatic diseases. The present documents summarize clinical studies with efficacy and satisfactory safety profile in which MSCs have been used for cell therapies in systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis.