Mesenterialarterienverschluss als seltene Komplikation bei Thrombangiitis obliterans

Pfitzmann, Robert; Nüssler, Natascha C.; Heise, Michael; Settmacher, Utz

doi:10.1007/s104-002-8035-2

Cited by 6 publications

(3 citation statements)

References 11 publications

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“…Selten können auch Gefäße viszeraler Organe betroffen sein, wie beispielsweise koronare, pulmonale, zerebrale oder intestinale Arterien [5, 6, 7]. Die zerebrale Manifestation wird nach ihren Erstbeschreibern auch als Spatz‐Lindenberg bezeichnet.…”

Section: Klinikunclassified

Thrombangiitis obliterans: Eine Übersicht

Hoeft

Kröger

Grabbe

et al. 2004

J Deutsche Derma Gesell

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Thromboangiitis obliterans is a vascular disease characterized by a segmental, non-atherosclerotic inflammation of the small and medium-sized arteries and veins. The vascular changes are mainly found on the distal extremities. Involvement of visceral organs is rare. Affected patients are mostly young male smokers, who develop ulcers and gangrene of the toes and fingers as a result of the vascular ischaemia. Diagnosis is made using characteristic clinical criteria as well as pathological findings in arteriography and histopathology. Although the exact underlying causes of Buerger's disease are still unknown, the disease is strongly associated with tobacco smoking. Although most investigators speculate about an autoimmune mechanism, no causative antigens have yet been discovered. The only definite form of therapy is the discontinuation of tobacco use. On the basis of smoking cessation, further therapies (e.g. administration of prostacyclin analoga) are possible. The mortality rate for patients with Buerger's disease is not higher than that for the rest of the adult population, but patients often require minor and major limb amputation due to ulcerations.

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Section: Klinikunclassified

Thrombangiitis obliterans: Eine Übersicht

Hoeft

Kröger

Grabbe

et al. 2004

J Deutsche Derma Gesell

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“…Tabelle 3 gibt einen Überblick über differenzialdiagnostisch relevante Begleiterkrankungen der akuten mesenterialen Ischämie, seltene Ursachen sind in Tabelle 5 zusammengefasst [47].…”

Section: äTiologieunclassified

Die akute mesenteriale Ischämie

Eckstein

2003

Chirurg

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Acute mesenteric ischemia represents an intensive medical emergency which, when untreated, leads to sepsis and multiorgan failure. Predictive factors for survival are the time duration between onset of symptoms and therapy, etiology,patient age, and immediate therapy with anticoagulants in case of acute mesenteric thrombosis. Pathologically raised laboratory parameters (lactate, acidosis, leukocytosis) are signs of advanced mesenteric ischemia. Therapy aims at reinstating arterial perfusion of ischemic and potentially life-threatening intestinal regions and at avoiding further ischemias or infarctions. Immediate vessel reconstruction (embolectomy, thrombectomy,TEA,bypass) can prevent mesenteric infarction and is therefore preferable to intestinal resection alone, as long as irreversible ischemia or sepsis are not present. If the degree of reperfusion is in question, the indication for "second-look laparotomy" is to be used generously.

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“…Die Thrombangitis obliterans (WiniwaterBuerger-Syndrom) ist eine Erkrankung mit letztendlich unklarer Genese, von der meist junge Männer mit starkem Nikotinkonsum betroffen sind; dieser Erkrankung liegt eine Entzündung der kleinen und mittleren Arterien und Venen zugrunde, die auch in selteneren Fällen die Mesenterialgefäße betreffen kann [1,25]. Unklare Bauchschmerzen bei jungen Männer mit starkem Nikotinkonsum sollten an diese seltene Differenzialdiagnose denken lassen [14,24,30].…”

Section: Chronisch-okklusive Mesenteriale Ischämieunclassified

Partielle Ischämien

Izbicki

Kastl

2003

Chirurg

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Partial mesenteric ischemia is defined as an incomplete occlusion of the superior mesenteric artery resulting in acute abdominal pain, distended abdomen,and bowel hypomotility on auscultation. This disease can be acute or chronic and is caused by vascular occlusion or non-occlusive mechanisms. CT scan and ultrasound show a thickening of the ischemic bowel wall. On endoscopy, initially mucosal edema is observed which may proceed to necrosis. Therapy modalities depend upon the clinical findings: prevailing acute abdominal pain and peritonitis result in emergency laparotomy; prevailing cramping abdominal pain without clinical signs of peritonitis allows time for further diagnostic steps such as mesenteric angiography and interventional procedures. Laparoscopy should be performed in exceptional situations only.

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Mesenterialarterienverschluss als seltene Komplikation bei Thrombangiitis obliterans

Cited by 6 publications

References 11 publications

Thrombangiitis obliterans: Eine Übersicht

Thrombangiitis obliterans: Eine Übersicht

Die akute mesenteriale Ischämie

Partielle Ischämien

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