Mesenteric desmoid tumor: De novo occurrence or recurrence following appendectomy?

Sullivan, Joshua L.; Chesley, Patrick M.; Nguyen, David

doi:10.1016/j.radcr.2021.10.028

Cited by 3 publications

(6 citation statements)

References 12 publications

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“…DTF within the abdominal region is a rare yet assertive benign tumor, accounting for a scant 0.03% of all tumors, predominantly occurring in the bowel's mesentery [3][4]. Typically affecting adults between 20 and 40, mesenteric DTF presents a notable gender disparity: women have a two-to three-fold higher likelihood of encountering this neoplasm than men [3,5].…”

Section: Discussionmentioning

confidence: 99%

“…The etiological factors predisposing to this tumor are not well known yet [4,6]. Multiple factors play a role in the pathogenesis of DFT, including physical, hormonal, and genetic factors [7].…”

Section: Etiologymentioning

confidence: 99%

“…On the other hand, sporadic cases rarely occur in the abdomen, representing only 5% of the cases and are commonly associated with some risk factors, including female gender, previous abdominal trauma or surgery, or high estrogen state due to hormonal treatment or pregnancy and childbirth [3]. Most published cases of mesenteric DTF had a preceding history of surgery or abdominal trauma [4].…”

Section: Etiologymentioning

confidence: 99%

“…Most of the symptoms caused by mesenteric DTF are nonspecific and commonly related to mass effect, as these tumors increase in size unnoticeably before becoming problematic causing pressure on adjacent organs including the bowel, solid organs, or vascular structures [4]. As highlighted in a study documented by Elisa Palladino and colleagues, there was an instance where a patient experienced acute pulmonary embolism due to the compression of the inferior vena cava by an expansive mesenteric desmoid tumor [6].…”

Section: Presentationmentioning

confidence: 99%

“…Still, failure to completely resect the mass might lead to a high recurrence rate, so resection with negative margins can reduce the rate of recurrence to 27% in comparison to 54% in cases with positive margins of resection [15]. The overall incidence of recurrence reaches 40% and it is especially higher in the first two years following resection [4,12,15]. Other risk factors that may increase the risk of recurrence include aggressive type of tumor, multicentric lesions, and FAP-related mesenteric DTF; it is advisable to provide imaging surveillance for these patients for up to 3 years using CT or MRI scan, then with US scan thereafter to detect any recurrence early on [4,5,14].…”

Section: Managementmentioning

confidence: 99%

See 4 more Smart Citations

A Sporadic Giant Mesenteric Desmoid-Type Fibromatosis in a Teenage Female: A Report of a Rare Case

Rabai,

Alrababah,

Batayha

et al. 2023

Cureus

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Mesenteric desmoid-type fibromatosis (DTF) is a rare benign yet aggressive neoplasm that has an unpredictable biological behavior ranging from spontaneous regression to extensive local infiltration and has a high tendency for recurrence. The presenting symptoms are usually nonspecific and mostly related to the large size of the tumor compressing adjacent organs. Imaging studies can be suggestive of the diagnosis, but confirmation is based on histopathological and immunohistochemical examination. The lack of knowledge on the etiology and pathogenetic behavior of this tumor leads to therapeutic and prognostic challenges. Future genetic studies may help in advancing our understanding of this neoplasm and in formulating the proper management and follow-up plan. Here we present a case of a 14-year-old female who presented to the emergency room complaining of diffuse abdominal pain and distention. A computed tomography (CT) scan showed a large mass occupying most of the abdominal cavity and compressing adjacent organs. Exploratory laparotomy with resection and anastomosis was performed, and the histopathological and immunohistochemical examination of the resected mass was consistent with mesenteric DTF.

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Section: Discussionmentioning

confidence: 99%

Section: Etiologymentioning

confidence: 99%

Section: Etiologymentioning

confidence: 99%

Section: Presentationmentioning

confidence: 99%

Section: Managementmentioning

confidence: 99%

See 3 more Smart Citations

A Sporadic Giant Mesenteric Desmoid-Type Fibromatosis in a Teenage Female: A Report of a Rare Case

Rabai,

Alrababah,

Batayha

et al. 2023

Cureus

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Occurrence of a desmoid tumour in a status post appendicectomy: A case report

Shastri,

Varma

2024

International Journal of Surgery Case Reports

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CT and MRI diagnostics of desmoid fibroids in familial colon adenomatosis

et al. 2022

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Objective: to study the features of CT and MRI diagnostics of desmoid fibroids (DF) in familial colon adenomatosis (SATC). Patients and methods: the study included 35 patients with desmoid fibroids (DF) in familial colon adenomatosis (SATC). All patients were examined using computed tomography (CT) and magnetic resonance imaging (MRI) with intravenous contrast. Localization, size, growth pattern, prevalence of DF, features of contrast and intensity of the MR signal on T2-VI and post-contrast T1-VI were evaluated. Twenty-five (71.4%) patients were observed in dynamics, including during systemic therapy. Results: in 21 (60.0 %) patients, a lesion of only one anatomical area was detected, and in 14 (40.0%) cases, a combined lesion of different anatomical zones was noted. In the majority of observations (33/35, 94.4 %) desmoid fibroids were detected in the mesentery and mesentery root of the small intestine, including with a combined lesion. The majority of patients (24/35, 68.6%) were diagnosed with a diffuse nodular form of growth; 13 (37.1%) had a nodular form and 6 (17.1%) had a diffuse form. Twenty-five patients (25/35, 71.4%) were repeatedly re-examined using CT (13/35, 37.1%) and MRI (12/35, 34.3%), in particular during systemic therapy. Conclusion: CT and MRI are the basic methods for detecting DF in SATC, allowing to determine the nature of tumor growth, to assess the prevalence of the tumor process and the degree of involvement of adjacent organs and structures. In dynamic observation and evaluation of the response of a desmoid tumor to systemic therapy, MRI has greater diagnostic capabilities compared to CT, since it takes into account not only the size of the desmoid, but also the intensity of the MR signal on T2-VI and the nature of the accumulation of contrast agent on post-contrast T1-VI with fat suppression.

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Mesenteric desmoid tumor: De novo occurrence or recurrence following appendectomy?

Cited by 3 publications

References 12 publications

A Sporadic Giant Mesenteric Desmoid-Type Fibromatosis in a Teenage Female: A Report of a Rare Case

A Sporadic Giant Mesenteric Desmoid-Type Fibromatosis in a Teenage Female: A Report of a Rare Case

Occurrence of a desmoid tumour in a status post appendicectomy: A case report

CT and MRI diagnostics of desmoid fibroids in familial colon adenomatosis

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