2018
DOI: 10.1039/c7tb02836a
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Mesoporous carbon hollow spheres: carbonisation-temperature-dependent delivery of therapeutic proteins

Abstract: This work reports the significance of the carbonisation temperature of mesoporous carbon hollow spheres (MCHS) in therapeutic protein delivery.

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Cited by 8 publications
(3 citation statements)
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“…The rationale for choosing 700 °C for the synthesis of MCHS is that with MCHS preparation under other 500 °C and 900 °C carbonation temperature conditions, we can obtain intact mesoporous hollow spherical structures, larger specific surface area, larger pore volume, higher carbon content, and suitable pore size. 21…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The rationale for choosing 700 °C for the synthesis of MCHS is that with MCHS preparation under other 500 °C and 900 °C carbonation temperature conditions, we can obtain intact mesoporous hollow spherical structures, larger specific surface area, larger pore volume, higher carbon content, and suitable pore size. 21…”
Section: Methodsmentioning
confidence: 99%
“…The rationale for choosing 700 1C for the synthesis of MCHS is that with MCHS preparation under other 500 1C and 900 1C carbonation temperature conditions, we can obtain intact mesoporous hollow spherical structures, larger specific surface area, larger pore volume, higher carbon content, and suitable pore size. 21 Preparation of Fe/Fe 3 C@MCHS Fe/Fe 3 C@MCHS was prepared using a simple one-step annealing method. Specifically, a mixture of 60 mg of carbon spheres and 60 mg of tannic acid in an equal proportion was added to 25 mL of deionized water and ultrasonically treated for 0.5 h. Then, 210 mg of ferric nitrate hydrate was dissolved in 5 mL of deionized water, stirred for 0.5 h, poured into the carbon sphere solution, and stirred again for 0.5 h. Afterward, 1.2 g of urea was added to the stirring solution and continued to stir for 0.5 h, and the solution was placed in an oven at 90 1C for overnight drying.…”
Section: Synthesis Of Mesoporous Carbon Hollow Spheres (Mchss)mentioning
confidence: 99%
“…investigated the impact of different types of N doping (pyrrolic, pyridinic, or graphitic) on the energy difference of excited singlet and triplet states, which is responsible for the oxygen photosensitization process . Yu and coworkers have shown a direct relationship between carbonization temperature and drug loading capacity in mesoporous carbon hollow spheres, while the influence of carbonization temperature on photothermal properties has been recently studied by our group . Although these papers describe dedicated efforts to control the nitrogen content and hence therapeutic performance of N-doped carbon materials, controlling the size and shape of NMCS to regulate their therapeutic activity has not been reported yet.…”
Section: Introductionmentioning
confidence: 99%