Mesoporous silica nanoparticles as a biomolecule delivery vehicle in plants

Hussain, Hashmath Inayath; Yi, Zhifeng; Rookes, James; Kong, Lingxue; Cahill, David M.

doi:10.1007/s11051-013-1676-4

Cited by 138 publications

(73 citation statements)

References 55 publications

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“…most of the root periderm, and all the aerial parts ( Figure 1). All kinds of NPs, such as negatively charged mesoporous silica nanoparticles (MSNs, 20 nm) (Hussain et al, 2013), or neutrally charged lipid-based liquid crystalline NPs (150-300 nm) (Nadiminti et al, 2013), were reported to accumulate above the anticlinal cell walls on or in the cuticle. In one case, nano-TiO 2 was shown to produce holes in the cuticle (Larue et al, 2014b).…”

Section: Cuticlementioning

confidence: 99%

“…All this underscores the role of stomata for NP deposition and uptake. Indeed, a wealth of studies documented stomata or substomatal chambers blocked by micrometer, submicrometer, and nano-sized particles Farmer, 1993;Hirano et al, 1995;Hussain et al, 2013;Uzu et al, 2010), and related adverse effects, particularly for mosses and lichens (Farmer, 1993;Hirano et al, 1995). Blocked stomata or guard cells can lead to reduced water transpiration, increased leaf temperature and then to reduced growth, photosynthesis and diffusive resistance (Farmer, 1993;Hirano et al, 1995).…”

Section: Stomata -Gas Transportersmentioning

confidence: 99%

“…From the xylem, NPs can distribute within the rest of the plant and be loaded into the phloem. Nanoparticles in the xylem have often been observed (Al-Salim et al, 2011;Corredor et al, 2009;Huang et al, 2011;Hussain et al, 2013;Marchiol et al, 2014;Wang et al, 2012b). Pits equipped with pit membranes in the tracheids mainly limit NP transport in the xylem vasculature, and primary pit fields in sieve areas are the bottlenecks of the phloem sieve cells (Fahn, 1982;Raven, 2003).…”

Section: Vasculaturementioning

confidence: 99%

“…The leaves are the sites where solutes transported via the xylem are transferred back into the symplast. In some cases, NPs were also shown to accumulate above, or in between the anticlinal cell walls of leaves (Hu et al, 2010;Hussain et al, 2013;Kole et al, 2013;Nadiminti et al, 2013). Thus, a growing body of evidence shows that NPs prefer to translocate through the apoplast.…”

Section: Vascular and Non-vascular Transport Processesmentioning

confidence: 99%

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Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants – Critical review

et al. 2015

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Uptake, transport and toxicity of engineered nanomaterials (ENMs) into plant cells are complex processes that are currently still not well understood. Parts of this problem are the multifaceted plant anatomy, and analytical challenges to visualize and quantify ENMs in plants. We critically reviewed the currently known ENM uptake, translocation, and accumulation processes in plants. A vast number of studies showed uptake, clogging, or translocation in the apoplast of plants, most notably of nanoparticles with diameters much larger than the commonly assumed size exclusion limit of the cell walls of ∼5-20 nm. Plants that tended to translocate less ENMs were those with low transpiration, drought-tolerance, tough cell wall architecture, and tall growth. In the absence of toxicity, accumulation was often linearly proportional to exposure concentration. Further important factors strongly affecting ENM internalization are the cell wall composition, mucilage, symbiotic microorganisms (mycorrhiza), the absence of a cuticle (submerged plants) and stomata aperture. Mostly unexplored are the roles of root hairs, leaf repellency, pit membrane porosity, xylem segmentation, wounding, lateral roots, nodes, the Casparian band, hydathodes, lenticels and trichomes. The next steps towards a realistic risk assessment of nanoparticles in plants are to measure ENM uptake rates, the size exclusion limit of the apoplast and to unravel plant physiological features favoring uptake.

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Section: Cuticlementioning

confidence: 99%

Section: Stomata -Gas Transportersmentioning

confidence: 99%

Section: Vasculaturementioning

confidence: 99%

Section: Vascular and Non-vascular Transport Processesmentioning

confidence: 99%

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Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants – Critical review

et al. 2015

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“…[2][3] A variety of sol-gel processes have been developed to synthesize ordered meso-structured silica frameworks with highly tuneable properties and morphologies from surfactant templates including parallel hexagonal meso-channels, radially oriented mesopores and hierarchical meso-structures. [4][5] The MSNs with particle size less than 30 nm in diameter [6][7][8] have higher permeability across biological cell membranes, better bio-compatibility and faster degradation than larger particles. [9][10][11] The appropriate understanding of the growth mechanism will provide useful knowledge to design and tailor particles of smaller size and unique porous morphology for a broad range of applications.…”

Section: Introductionmentioning

confidence: 99%

A New Insight into Growth Mechanism and Kinetics of Mesoporous Silica Nanoparticles by in Situ Small Angle X-ray Scattering

Dumée

Garvey

et al. 2015

Langmuir

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The growth mechanism and kinetics of mesoporous silica nanoparticles (MSNs) were investigated for the first time by using a synchrotron time-resolved small-angle X-ray scattering (SAXS) analysis. The synchrotron SAXS offers unsurpassed time resolution and the ability to detect structural changes of nanometer sized objects, which are beneficial for the understanding of the growth mechanism of small MSNs (∼20 nm). The Porod invariant was used to quantify the conversion of tetraethyl orthosilicate (TEOS) in silica during MSN formation, and the growth kinetics were investigated at different solution pH and temperature through calculating the scattering invariant as a function of reaction time. The growth of MSNs was found to be accelerated at high temperature and high pH, resulting in a higher rate of silica formation. Modeling SAXS data of micelles, where a well-defined electrostatic interaction is assumed, determines the size and shape of hexadecyltrimethylammonium bromide (CTAB) micelles before and after the addition of TEOS. The results suggested that the micelle size increases and the micelle shape changes from ellipsoid to spherical, which might be attributed to the solubilization of TEOS in the hydrophobic core of CTAB micelles. A new "swelling-shrinking" mechanism is proposed. The mechanism provides new insights into understanding MSN growth for the formation of functional mesoporous materials exhibiting controlled morphologies. The SAXS analyses were correlated to the structure of CTAB micelles and chemical reaction of TEOS. This study has provided critical information to an understanding of the growth kinetics and mechanism of MSNs.

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Energy Storing Plant Stem with Cytocompatibility for Supercapacitor Electrode

Liang

Liu

et al. 2021

Adv Funct Materials

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Endowing natural biological objects, such as plants or their parts, with non-native and targeted electroactivity is an appealing challenge in nanobiotechnology, which if addressed will circumvent the biomass carbonization and promote the emission-free transformation of raw bioresources for green energy. Here, a general concept to produce supercapacitor electrodes from plant stems is reported, which exhibit promising electroactivity and cytocompatibility. The core innovation is to apply a conformal electroactive coating onto the surfaces of hyperbranched channels of plant stem by interfacial self-assembly. The electroactive plant stem can be employed as a functional supercapacitor electrode, the capacitance of which is up to 2.35 F. Furthermore, more than 98% cell viability is well maintained after the plant stem electrode is incubated with MCF-7 cells for 72 h, and even after 100 discharge-recharge cycles, suggesting this plant stem electrode has excellent cytocompatibility and cycling stability. This energy storing plant stem gives rise to new opportunities for integrating natural bioresources with artificial electroactive nanomaterials for cytocompatible energy storage devices.

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Mesoporous silica nanoparticles as a biomolecule delivery vehicle in plants

Cited by 138 publications

References 55 publications

Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants – Critical review

Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants – Critical review

A New Insight into Growth Mechanism and Kinetics of Mesoporous Silica Nanoparticles by in Situ Small Angle X-ray Scattering

Energy Storing Plant Stem with Cytocompatibility for Supercapacitor Electrode

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