Meta-Analysis Comparing Risk Factors, Incidence, and Outcomes of Patients With Versus Without Prosthesis-Patient Mismatch Following Transcatheter Aortic Valve Implantation

Lim, Oliver Zi Hern; Shengting, Aaron; Ng, Chin Hin; Tang, Ansel Shao Pin; Chin, Yip Han; Kong, Gwyneth; Ho, Yeung Jek; Ong, J L; Tay, Edgar; Kuntjoro, Ivandito; Chew, Nicholas; Lim, Yinghao

doi:10.1016/j.amjcard.2022.01.023

Cited by 5 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The impact of PPM on long-term prognosis has been reported. 20 In this study, the follow-up was only 1 year, and it is unclear how much PPM affects prognosis. Future long-term follow-up is also important.…”

Section: Discussionmentioning

confidence: 81%

“… 18 TAVI of the bicuspid valve is challenging because of severe calcification and anatomic uniformity, which can lead to insufficient expansion of the THV and a smaller EOA index. Although PPM has been reported to be associated with a poor prognosis, 19 , 20 it cannot be a determinant of prognosis in Japanese patients. 21 In our study, PPM was also higher in some patients in the very severe AS group; however, their prognosis at 1 year was not significantly different from that of patients in the severe AS group.…”

Section: Discussionmentioning

confidence: 91%

See 1 more Smart Citation

Feasibility of Transcatheter Aortic Valve Implantation in Patients With Very Severe Aortic Stenosis

et al. 2023

View full text Add to dashboard Cite

Background: Very severe aortic stenosis (AS) has a poor prognosis even in asymptomatic patients, and asymptomatic very severe AS is a Class IIa indication for aortic valve replacement, although the safety and effectiveness of transcatheter aortic valve implantation (TAVI) for very severe AS is not well-established. Methods and Results: This study included 366 patients undergoing TAVI at a single center, with 85 and 281 patients in the very severe AS (peak velocity ≥5 m/s or mean pressure gradient (PG) ≥60 mmHg) and severe AS groups, respectively. Procedural and clinical outcomes at 1-year follow-up were compared between groups. The calcium scores were significantly higher in the very severe AS group (2,864.5 vs. 1,405.8 arbitrary units [AU] (P<0.001). Although the patient-prosthesis mismatch rate was higher in the very severe AS group (38.3% vs. 25.7%; P=0.029), there was no significant difference in the early safety and clinical efficacy between the groups (16.5% vs. 17.1% and 12.0% vs. 18.9%, respectively). Similarly, there was no significant difference in all-cause mortality at 1 year (4.8% vs. 9.8%). Conclusions: Despite a higher incidence of prosthesis–patient mismatch in those with very severe AS, the procedural and clinical outcomes were comparable to those in patients with severe AS. TAVI may be a reasonable treatment option for very severe AS.

show abstract

Section: Discussionmentioning

confidence: 81%