2016
DOI: 10.1007/s00590-016-1846-z
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Meta-analysis of epidural analgesia versus peripheral nerve blockade after total knee joint replacement

Abstract: Background Postoperative pain after major knee surgery can be severe. Our aim was to compare the outcomes of epidural analgesia and peripheral nerve blockade (PNB) in patients undergoing total knee joint replacement (TKR). Moreover, we aimed to compare outcomes of adductor canal block (ACB) with those of femoral nerve block (FNB) after TKR.Methods We conducted a systematic search of electronic information sources, including MEDLINE; EMBASE; CINAHL; and the Cochrane Central Register of Controlled Trials (CENTRA… Show more

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Cited by 31 publications
(31 citation statements)
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“…Although general or spinal anesthesia is usually selected for ORIF of hip fracture, both methods can cause hypotension in approximately one-third of patients [7]. By contrast, FNB, which has less of an effect on the sympathetic nerves, is expected to impact blood pressure to a lesser extent than spinal anesthesia [8][9][10]. Notably, decreased systemic vascular resistance due to anesthesia is associated with a high risk of an increased pressure gradient across the LVOT, which may create a stronger Venturi effect [4,5,11].…”
Section: Discussionmentioning
confidence: 99%
“…Although general or spinal anesthesia is usually selected for ORIF of hip fracture, both methods can cause hypotension in approximately one-third of patients [7]. By contrast, FNB, which has less of an effect on the sympathetic nerves, is expected to impact blood pressure to a lesser extent than spinal anesthesia [8][9][10]. Notably, decreased systemic vascular resistance due to anesthesia is associated with a high risk of an increased pressure gradient across the LVOT, which may create a stronger Venturi effect [4,5,11].…”
Section: Discussionmentioning
confidence: 99%
“…A femoral nerve block has a smaller effect on hemodynamic parameters than spinal-epidural anesthesia. This hemodynamic instability with spinal-epidural anesthesia is mainly induced by the sympathetic block [46]. For patients with severe aortic stenosis, it is important to maintain afterload in order to preserve coronary artery blood flow [7].…”
Section: Discussionmentioning
confidence: 99%
“…Die Analyse großer Patientenkollektive zeigte die tatsächlichen Risiken bei neuroaxialen Blockaden, insbesondere bei der Anwendung von Epiduralkathetern in bestimmten Patientenkollektiven [21][22][23]. So existiert für die Regionalanästhesie im Rahmen der Knieendoprothetik mit der Blockade peripherer Nerven heute eine im Vergleich zur Epiduralanästhesie gleich wirksame und sichere Alternative [24].…”
Section: Neue Optionen Durch Faszienblockadenunclassified