Meta-analysis of neonicotinoid insecticides in global surface waters

Abstract

Neonicotinoids (NEOs) are a class of insecticides that have high insecticidal activity and are extensively used worldwide. However, increasing evidence suggests their long-term residual in the environment and toxic effects on nontarget organisms. NEO residues are frequently detected in water and consequently have created increasing levels of pollution and pose signi cant risks to humans. Many studies have conducted surveys of NEO concentrations in water; however, few studies have focused on global systematic reviews or meta-analyses of NEO concentrations in water. In the present study, 43 published papers from 10 countries were indexed for a meta-analysis of the global NEO distribution in water. Among these studies, most focus on eastern Asia and North America, which are involved in intensive agricultural activities. The order of mean concentrations is identi ed as imidacloprid (119.542 ± 15.656 ng L −1 ) > nitenpyram (88.076 ± 27.144 ng L −1 ) > thiamethoxam (59.752 ± 9.068 ng L −1 ) > dinotefuran (31.086 ± 9.275 ng L −1 ) > imidaclothiz (24.542 ± 2.906 ng L −1 ) > acetamiprid (23.360 ± 4.015 ng L −1 ) > thiacloprid (11.493 ± 5.095 ng L −1 ). Moreover, the relationship between NEO concentrations and some environmental factors is analyzed. NEO concentrations increase with temperature, oxidation-reduction potential and the percentage of cultivated crops but decrease with stream discharge, pH, dissolved oxygen and precipitation. NEO concentrations show no signi cant relations to turbidity and conductivity.The purpose of this review is to conduct a meta-analysis on the concentration of NEOs in global waters based on published detections from several countries to extend knowledge on the application of NEOs.

Melatonin Supplementation during In Vitro Maturation of Porcine Oocytes Alleviates Oxidative Stress and Endoplasmic Reticulum Stress Induced by Imidacloprid Exposure

“…Neonicotinoid insecticides are the most widely used synthetic insecticides in the world [ 24 ]. Due to their water solubility and long-term persistence in the environment, they have caused serious environmental problems [ 25 ]. Insecticides can enter the body through ingestion, inhalation, or skin contact [ 26 , 27 ].…”

Characterization of Complexes between Imidacloprid and β-Cyclodextrin: Evaluation of the Toxic Activity in Algae and Rotifers

“…Considering that the IMI acute EC50 value was definitely above the concentrations of environmental concern, going from hundredths of nanomoles/L to tenths of micromoles/L [ 26 , 28 , 39 , 40 , 41 ], and that the aquatic organisms are exposed to IMI residues for a prolonged period of time, we decided also to evaluate the long-term toxicity.…”

Toxicity of the neonicotinoid insecticides thiamethoxam and imidacloprid on tadpoles of four species of South American amphibians and effects of thiamethoxam on the metamorphosis of Rhinella arenarum

“…Overall, the toxicity data obtained in this study indicates that, as previously concluded for sh, IMI and TIA do not present a risk of acute or subchronic mortality for amphibians in larval stages in nature, because the concentrations causing mortality (Tables 1 and 2) are well above the concentrations normally reported in aquatic environments. Indeed, these usually range between 0.004-9140 ng/L (mean 119.5 ng/L) for IMI and 0.002-3820 ng/L (mean 59.7 ng/L) for TIA, according to a recent meta-analysis of worldwide eld data (Wang et al, 2022). Similarly, in the Pampa region, the highest concentrations of IMI measured so far were 430 and 560 ng/L (Caprile, 2019;Perez et al, 2017), while no values were found for aquatic concentrations of TIA in the Pampa.…”