Meta-analysis of randomized clinical trials on the speed of pulse wave propagation

Abstract

This paper presents a theoretical analysis of the literature on the speed of pulse wave propagation using a combination of ECG and PPG signals. The diagnostic value of pulse wave velocity in medical practice is use of this indicator for non-invasive measurement of blood pressure and also for determination of arterial stiffness. Some studies have shown an association of pulse wave velocity with risk factors for cardiovascular disease. The speed of pulse wave propagation is an early marker and predictor of cardiovascular risk both in individuals with normal blood pressure and people with hypertension and is used as the "gold standard" for assessing arterial stiffness; however, the question about accuracy and automation of the measurement of the speed of pulse wave propagation still remains to be answered.