Meta-analysis of the clinical efficacy and safety of oblique lateral interbody fusion and transforaminal interbody fusion in the treatment of degenerative lumbar spondylolisthesis

Abstract

Objective The aim of this study was to comprehensively evaluate the efficacy of oblique lateral interbody fusion (OLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of degenerative lumbar spondylolisthesis by meta-analysis. Methods A computer-based search of PubMed, Cochrane Library, Embase, Web of Science Core Collection databases, the China National Knowledge Infrastructure, China Biology Medicine, and Wanfang Digital Periodicals was conducted from the time of inception of each database to December 2021. The review process was conducted according to the PRISMA guidelines and registered in the PROSPERO database. Meta-analysis was performed using RevMan 5.4 software provided by the Cochrane Library. Results Thirteen studies were included in the statistical analysis. One randomized controlled study and 12 cohort studies with 954 patients were included. In terms of operation time, intraoperative blood loss, Oswestry disability index score, intervertebral height, and complications, the OLIF group was better than the TLIF group, and the difference was statistically significant (P < 0.05). There was no significant difference between the two groups in terms of visual analogue scale score, lumbar lordosis or fused segment lordosis (P > 0.05). Conclusion Both OLIF and TLIF are effective surgical modalities in the treatment of degenerative lumbar spondylolisthesis. They achieve similar therapeutic effects, but OLIF is superior to TLIF in restoring intervertebral height. At the same time, OLIF has the advantages of short operation time and less intraoperative blood loss.

Management for degenerative lumbar spondylolisthesis: a network meta-analysis and systematic review basing on randomized controlled trials

“…NS options include oral and injectable pain medications and physical therapy. In contrast, surgical options include decompression only (DO), decompression plus fusion without internal fixation (DF), decompression plus fusion with internal fixation (DFI), endoscopic decompression plus fusion (EDF), endoscopic decompression (ED), and circumferential fusion (360F) 2 , 8 – 11 . However, the efficacy of different treatment strategies remains controversial 3 , 12 , 13 .…”

Comparing OLIF Combined with Lateral Screw Fixation versus Minimally Invasive TLIF for Treating Single-Level Degenerative Lumbar Spondylolisthesis: A Retrospective Cohort Study

“…33 Although it is an indirect decompression modality, OLIF has been shown to be clinically equivalent to Mis-TLIF for the treatment of DLS and DLSS. [15][16][17][18][19][20][21][22][23][24][25][26][27][28] OLIF was performed through an oblique lateral approach. The intervertebral disk nucleus pulposus and cartilaginous endplate were thoroughly removed.…”

“…[11][12][13][14] To date, some studies have compared the clinical and radiologic outcomes of OLIF with Mis-TLIF or TLIF in patients with DLS or degenerative lumbar spinal stenosis (DLSS). [15][16][17][18][19][20][21][22][23][24][25][26][27][28] Although clinical efficacy comparable to Mis-TLIF or TLIF can be achieved, most studies have reported that posterior fixation is often required after OLIF to reduce the risk of cage displacement or subsidence. 29 However, compared with lateral fixation, posterior fixation can significantly increase OT and surgical trauma, thus making the surgery more cumbersome.…”

The efficacy and safety of tranexamic acid in transforaminal lumbar interbody fusion: a systematic review and meta-analysis

“…Transforaminal lumbar interbody fusion (TLIF) is a surgical method widely used to treat spinal diseases such as herniated discs, lumbar spondylolisthesis, and lumbar stenosis ( 1 , 2 , 3 ). With the rapid development of aging society and the influence of modern lifestyles, the incidence of these spinal diseases is gradually increasing.…”