2017
DOI: 10.5301/jbm.5000236
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Meta-Analysis Reveals no Significant Association between ERCC6 Polymorphisms and Bladder Cancer Risk

Abstract: According to the results of our meta-analysis, there is no evidence of a link between the ERCC6 gene polymorphisms and bladder cancer risk. Well-designed further studies, with larger sample sizes and adjustment for confounders such as smoking status, are needed to confirm these conclusions.

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(1 citation statement)
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“…Moreover, rs1800629 in TNF-α [270,271] and rs833061 in VEGFA [122] also showed no association with BC in a meta-analysis. Rs4253211 in ERCC6 [272], rs1042489 in BIRC5 [216] and rs4880 in SOD2 [273] were also not associated with BC. Finally, rs11225395, rs35866072, and rs1940475 in MMP8 [274], as well as rs3918242 [243,244,275], rs3918241, rs2250889, rs17576, and rs17577 in MMP9 all showed no association with any risk for carcinogenesis [276].…”
Section: Not Associated Snpsmentioning
confidence: 86%
“…Moreover, rs1800629 in TNF-α [270,271] and rs833061 in VEGFA [122] also showed no association with BC in a meta-analysis. Rs4253211 in ERCC6 [272], rs1042489 in BIRC5 [216] and rs4880 in SOD2 [273] were also not associated with BC. Finally, rs11225395, rs35866072, and rs1940475 in MMP8 [274], as well as rs3918242 [243,244,275], rs3918241, rs2250889, rs17576, and rs17577 in MMP9 all showed no association with any risk for carcinogenesis [276].…”
Section: Not Associated Snpsmentioning
confidence: 86%