Optimizing vessel hull resistance is pivotal for enhancing maritime performance and minimizing environmental impacts. Traditional methods combine expert intuition with Data-Driven Models (DDMs), relying on parametrization to predict and optimize hull geometries using Experimental Fluid Dynamics (EFD) or Computational Fluid Dynamics (CFD) data. However, these conventional approaches are hampered by several limitations: they require significant human input, are computationally intensive and costly, and lack flexibility in adapting to new families of geometries or parameters beyond predefined ranges. Addressing these challenges, our research introduces a novel method that significantly reduces the need for human intervention, computational resources, and costs, while also improving the model's adaptability. By proposing a new a parametrization technique that accurately encompasses the Delft Systematic Yacht Hull Series (DSYHS), we demonstrate that DDMs can be effectively trained directly on EFD datasets. This eliminates the dependency on extensive CFD simulations or the generation of new EFD data tailored to a specific investigation. Our approach matches the performance of leading-edge CFD models, even in extrapolating conditions, with physical plausibility and minimal human oversight. The validation of our method under various and increasingly complex extrapolating scenarios, employing statistical analyses on the DSYHS EFD dataset and comparisons with state-of-the-art CFD models, underscores the effectiveness of our proposal. Furthermore, we demonstrated that our model can successfully optimize hull resistance when navigating geometric parameters outside the confines of the DSYHS validating our results through leading-edge CFD simulations. This work addresses the limitations of existing methodologies by offering a novel approach more accurate, efficient, cost-effective, flexible, automated, and robust to extrapolation for hull resistance optimization.