Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population

Charles-Davies, Mabel Ayebatonyo; Fasanmade, Adesoji Adedipe; Olaniyi, John Ayodele; Oyewole, Oyediran Emmanuel; Owolabi, Mayowa; Adebusuyi, Jane Roli; Hassan, O.; Ajobo, M. T.; Ebesunun, M O; Adigun, Kehinde; Akinlade, Kehinde Sola; Fabian, Unyime Aniekpon; Popoola, O. O.; Rahamon, Sheu Kadiri; Okunbolade, Wemimo; Ogunlakin, Matthew; Arinola, OG; Agbedana, E O

doi:10.1155/2013/351357

Cited by 12 publications

(14 citation statements)

References 13 publications

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“…Reported participation rates ranged from 75 to 100%. The age of the workers ranged from 15 years old civil servants ( 85 ) to 105 years old traders ( 38 ). In 32 reporting studies, the mean ages ranged from 23.2 years among policemen ( 52 ) to 63.0±12.6 years among rural farmers ( 70 ).…”

Section: Resultsmentioning

confidence: 99%

“…A slightly higher proportion of studies among informal sector workers reported a prevalence ≥30% than those among formal sector workers (6/15 vs. 9/23 studies). High prevalence (≥30%) informal sector workers included traders ( 38 , 39 ), market workers ( 86 ), music shop operators, and chiefs ( 77 ). Among formal sector workers, they included civil servants ( 30 , 48 , 56 ), health workers ( 62 , 80 ), university staff ( 60 ), port workers ( 76 ), factory workers ( 46 ), senior executives ( 68 ), and telecommunications workers ( 69 ).…”

Section: Resultsmentioning

confidence: 99%

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The prevalence, awareness, and control of hypertension among workers in West Africa: a systematic review

Bosu

2015

Global Health Action

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BackgroundInterventions in workplace settings are considered to be cost-effective in preventing cardiovascular diseases. A systematic review was conducted to assess the prevalence of hypertension and the level of awareness and control among workers in West Africa.DesignA systematic search for studies on formal and informal sector workers aged ≥15 years in West Africa published between 1980 and September 2014 was undertaken using the Ovid Medline, Embase, PubMed, and Google Scholar databases. Clinical and obstetric studies and studies that did not report prevalence were excluded. Data on study settings, characteristics of workers, blood pressure (BP) levels, prevalence of hypertension, and associated demographic factors were extracted.ResultsA total of 45 studies from six countries were identified involving 30,727 formal and informal sector workers. In 40 studies with a common definition of hypertension, the prevalence ranged from 12.0% among automobile garage workers to 68.9% among traditional chiefs. In 15 of these studies, the prevalence exceeded 30%. Typically sedentary workers such as traders, bank workers, civil servants, and chiefs were at high risk. Among health care workers, the prevalence ranged from 17.5 to 37.5%. The prevalence increased with age and was higher among males and workers with higher socio-economic status. Complications of hypertension, co-morbidities, and clustering of risk factors were common. The crude prevalence of hypertension increased progressively from 12.9% in studies published in the 1980s to 34.4% in those published in 2010–2014. The proportion of hypertensives who were previously aware of their diagnosis, were on treatment or had their BP controlled was 19.6–84.0%, 0–79.2%, and 0–12.7%, respectively. Hypertensive subjects, including health workers, rarely checked their BP except when they were ill.ConclusionsThere is a high prevalence of hypertension among West Africa's workforce, of which a significant proportion is undiagnosed, severe or complicated. The clustering of risk factors, co-morbidities, and general low awareness warrant an integrated and multisectoral approach. Models for workplace health programmes aiming to improve cardiovascular health should be extended to informal sector workers.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The prevalence, awareness, and control of hypertension among workers in West Africa: a systematic review

Bosu

2015

Global Health Action

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“…Similar to our findings, several studies have shown that the prevalence rates and other BP parameters were significantly higher in men . However, some studies have found that these BP parameters were higher in women, especially in those with a cluster of cardiometabolic risk factors . This may be explained by the presence of concomitant cardiovascular risk factors, which are often neglected in women.…”

Section: Discussionmentioning

confidence: 99%

“…23,25 However, some studies have found that these BP parameters were higher in women, especially in those with a cluster of cardiometabolic risk factors. 26,27 This may be explained by the presence of concomitant cardiovascular risk factors, which are often neglected in women. Despite sharp increases in patient awareness and antihypertensive treatment, BP control remains low.…”

Section: Discussionmentioning

confidence: 99%

Sex Disparity in Blood Pressure Levels Among Nigerian Health Workers

Adeoye

Adebiyi

Owolabi

et al. 2015

J of Clinical Hypertension

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Gender disparity in hypertension prevalence is well established in developed nations; however there is paucity of data on the distribution of hypertension prevalence between genders in developing countries. We therefore examined gender differences in hypertension prevalence and cardiovascular risk factors in a sample of 352 healthy hospital workers in Nigeria. Mean ages of men and women were 37.2±7.9 and 44.7±9.1 years respectively. Thirty- five percent of participants were hypertensive with 54% on treatment and 70% had controlled blood pressure. Men had higher prevalence of hypertension (38.4% vs 33.0%) and prehypertension (37.6% vs 29.7%). Women had significantly higher odds of developing hypertension and of being on treatment. Mean blood pressure and fasting plasma glucose were higher in men while women were older, obese, dyslipideamic and had lower mean estimated GFR(p<0.0001). These findings indicate gender disparity in blood pressure among hospital employees; gender focused management of hypertension is therefore advocated for hospital employees.

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“…SBP had a positive relationship with FSH in the cases only (P<0.05) in this study. Blood pressure is known to increase in MS, with age and with increasing measures of adiposity-known cardiovascular risk factors (Charles-Davies et al, 2013). Moreover, higher FAI, a surrogate marker of free testosterone in cases than controls was demonstrated (P<0.05).…”

Section: Discussionmentioning

confidence: 92%

Reproductive function in premenopausal African Blacks with metabolic syndrome: Associations among inhibin B, adipokines, pituitary and sex hormones and sex hormone binding globulin

Famuyiwa¹,

Bitrus²,

Charles-Davies³

et al. 2016

Int. J. Med. Med. Sci.

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Reproductive dysfunction is associated with metabolic syndrome. Since fertility is highly valued in Africa, preliminary data on the association of metabolic syndrome with indices of reproductive function in premenopausal Nigerian women was provided. Sixty six premenopausal participants (44 with metabolic syndrome and 22 controls) aged 18-45 years were purposely selected for this study. Reproductive history, blood pressure and waist circumference were obtained by standard methods. Fasting blood was obtained for pituitary hormones, adipokines, sex hormone and sex hormone binding globulin, and inhibin B assays by EIA, ELISA and electro-chemiluminiscence. Plasma glucose, triglycerides and high density lipoprotein cholesterol were estimated by enzymatic methods. Free androgen index and oestrogen-testosterone ratio were calculated. Data obtained were statistically significant at P<0.05. All reproductive factors except follicle stimulating hormone and free androgen index levels were similar in both groups (P>0.05). Leptin levels were higher while adiponectin levels were lower in MS group than controls (P<0.05). Reproductive function appears sustained in MS. However, altered adipokines may relate to MS.

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Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population

Cited by 12 publications

References 13 publications

The prevalence, awareness, and control of hypertension among workers in West Africa: a systematic review

The prevalence, awareness, and control of hypertension among workers in West Africa: a systematic review

Sex Disparity in Blood Pressure Levels Among Nigerian Health Workers

Reproductive function in premenopausal African Blacks with metabolic syndrome: Associations among inhibin B, adipokines, pituitary and sex hormones and sex hormone binding globulin

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