Metabolic and hormonal changes during and after exchange transfusion with heparinized or ACD blood

Effect of Blood Transfusion on Acid Base, Glucose and Electrolyte Status in Very Low Birth Weight Infants

“…Indeed exchange transfu sion using citrated blood results in rebound hypoglycaemia, a reaction to hyperglycaemic blood during the procedure [7,8]. However, the slow rate of transfusion in the present study as well as the relatively small amount of blood transfusion ensured that the rate of infusion of glucose was indeed negligible, less than the rate of glucose consumption of the infants.…”

“…The effect of citrate phosphate dextrose (CPD) blood transfusion on the acid base, glucose and electrolyte status of VLBW infants was studied in infants aged [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] and > 20 days; a 4th group composed of infants > 20 days subjected to a second transfusion was also studied. All the infants remained clinically well during and after the transfusion.…”

Metabolic and Hormonal Consequences of Exchange Transfusion via the Umbilical Artery or Vein

“…If blood preserved with acid citrate and dextrose (ACD) is used, problems of acid-base balance, blood glucose homeostasis and lowered ionized calcium levels may result (2,8,9) whereas if heparin is em ployed there may be complications due to anticoagulation and excessive rise following transfusion in unconjugated unbound bilirubin (3). The work reported here was undertaken to investigate which route of transfusion was better for glucose homeostasis and which was the less stressful.…”

Neonatal exchange transfusion with heparinised whole blood or citrated composite blood: a prospective study

“…Having started feeds with a polymeric formula, the baby started vomiting and it is hypothesized that vomiting combined with the predisposition to mucosal damage was the cause of GP. The mild eosinophilia invokes another risk factor for GP with the possibility of an allergic gastropathy brought on by the polymeric formula [2,5]. There is merit in suggesting the use of semi-elemental formula in children after major bowel surgery but it should also be considered for use after other procedures, such as cardiac surgery, if bowel ischemia is suggested.…”