Metabolic Changes in Obesity

Abstract

The exact basis for the increase in global obesity rates is complex, so obesity should not be simply viewed as a biochemical problem of energy imbalance. While imbalance in energy metabolism is the main cause of obesity, only 5% of patients return to a normal weight after the incorporation of dietary changes. Eating behavior is enormously complex. It is governed by brain biochemistry influenced by many interdependent peptides or lipids. Excess body fat is the defining characteristic of this disorder, linked to the occurrence of a number of metabolic irregularities, which lead to other health problems. Adipose tissue plays an essential role in the metabolic process of energy balance, essential for understanding the phenomena associated with obesity.