Metabolic consequences of sigmoidocystoplasty in children

Abstract

Recent reports have shown that metabolic acidosis is a possible complication in patients who undergo augmentation enterocystoplasty. We studied 30 patients with neurogenic bladder who underwent sigmoidocystoplasty. Follow-up ranged from 1 to 10 years; all the patients showed normal renal function. We found significant hyperchloremic acidosis in 10% and borderline acidosis in 27% of the patients. Abnormalities of calcium and phosphorus balance were noted in 16.5% and 43% of the patients respectively, and more frequently in acidolic patients, which might be the result of activation of the bony buffers and might cause delayed growth in children. Close follow-up of all patients with enterocystoplasty is required, and oral bicarbonate is indicated when acidosis is detected.

Pediatric Urinary Tract Reconstruction Using Intestine

“…Alternative methods to deal with these problems include augmentation or replacing of the bladder. When performing urinary tract reconstruction with intestine, well-known consequences include acidosis, anemia, impaired renal function, poor growth and osteomalacia (2)(3)(4)(5). Surgical procedures in these patients therefore require consistent follow-up over a long period of time to allow early detection of detrimental consequences for the renal function and late metabolic effects.…”