2014
DOI: 10.1007/s11892-014-0507-z
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Metabolic Consequences of Sleep and Circadian Disorders

Abstract: Sleep and circadian rhythms modulate or control daily physiological patterns with importance for normal metabolic health. Sleep deficiencies associated with insufficient sleep schedules, insomnia with short-sleep duration, sleep apnea, narcolepsy, circadian misalignment, shift work, night eating syndrome and sleep-related eating disorder may all contribute to metabolic dysregulation. Sleep deficiencies and circadian disruption associated with metabolic dysregulation may contribute to weight gain, obesity, and … Show more

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Cited by 377 publications
(270 citation statements)
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References 96 publications
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“…circadian rhythm sleep disorder and sleep apnea) and shift workers have been shown to elevate the risk of both metabolic and psychiatric disorders, including obesity, type-2 diabetes, depression, and suicide [26][27][28][29][30][31]. Therefore, we hypothesize that the circadian clock system may serve as a central modulator of higher brain functions and metabolism by coordinating key systems and physiological processes, such as the reward system, the stress response, and energy utilization;…”
Section: Disturbed Circadian Clocks As the Basis Of Metabolic And Psymentioning
confidence: 98%
“…circadian rhythm sleep disorder and sleep apnea) and shift workers have been shown to elevate the risk of both metabolic and psychiatric disorders, including obesity, type-2 diabetes, depression, and suicide [26][27][28][29][30][31]. Therefore, we hypothesize that the circadian clock system may serve as a central modulator of higher brain functions and metabolism by coordinating key systems and physiological processes, such as the reward system, the stress response, and energy utilization;…”
Section: Disturbed Circadian Clocks As the Basis Of Metabolic And Psymentioning
confidence: 98%
“…En referencia a la relación entre los Trastornos del sueño y el Síndrome, la mayoría de las publicaciones refieren que el Insomnio tanto de inicio como de mantenimiento tiende a estar presente entre estos pacientes (11,16,32).…”
Section: Trabajo De Fin De Gradounclassified
“…Por otra parte, aunque la asociación que se establece entre el NES y el ritmo sueño-vigilia parece incierta, la mayor evidencia parece indicar que dicho ciclo permanece inalterado (7,24,32).…”
Section: Trabajo De Fin De Gradounclassified
“…Given that hypocretin is thought to influence mesolimbic dopamine signaling, absence of hypocretin could result in dysfunction in reward circuits and consequent daytime and nocturnal impulsive behaviors [21]. On the other hand, there is considerable data showing that sleep disruptions and sleepiness in otherwise healthy subjects are associated with poorer food choices that are higher in caloric density [22] and sugar content [23]. In any case, childhood obesity is associated with a number of well-known long-term metabolic and cardiovascular health consequences, and thus, close monitoring of weight and eating behaviors is important in clinical management of pediatric narcolepsy.…”
Section: Obesity and Precocious Puberty Obesitymentioning
confidence: 99%