Metabolic Differences between Dietary Liquid Glucose and Sucrose

Allen, R. J. L.; Brook, Matthew S.; Lister, R. E.; Sim, Andre; Warwick, M. H.

doi:10.1038/2111104a0

Cited by 12 publications

(2 citation statements)

References 11 publications

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“…In previous studies where dietary carbohydrate was supplied by different sugars, metabolic processes were affected appreciably. Allen et al (1966) and Allen and Leahy (1966) showed that diets containing sucrose or fructose fed to laboratory rats increased plasma cholesterol concentrations and fat in skeletal muscle and liver when compared with isocaloric diets containing dextrose or liquid glucose. Further, the sucrose and fructose diets increased concentration of lipids in serum and this was associated with an increase in deposition of abdominal fat.…”

Section: Discussionmentioning

confidence: 99%

Yield and Composition of Milk and Weight Gain of Nursing Pigs from Sows Fed Diets Containing Fructose or Dextrose

White¹,

Head²,

Bachman³

et al. 1984

Journal of Animal Science

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Yield and composition of milk and growth of nursing pigs in response to dietary treatment were estimated from 25 lactating sows during a 22-d period. Eight sows were fed 6 kg/d of a corn-soybean control diet (C sows). Nine were fed the control diet in which approximately 6.5 g X kg body weight (BW-1) X d-1 of carbohydrate was supplied by fructose corn syrup (F sows) and eight were fed the control diet containing equivalent carbohydrate supplied by powdered dextrose (D sows). Blood samples collected via jugular cannulae were analyzed for plasma concentrations of fructose, glucose and insulin. Concentrations of fructose and glucose from F sows were significantly higher throughout the study than that from D and C sows, while insulin concentration was approximately 2.5-fold lower. Milk yield from F sows on d 14 and 21 was significantly higher and pigs weaned on d 21 were heavier than those from D and C sows. Sows fed the diet containing fructose experienced significant BW loss during lactation. Coefficients of gross correlation across treatments showed milk yield and litter weight gain to be negatively associated with percentages of protein, lipids and total solids in milk, but positively associated with concentrations of lactose and gross energy. Nursing pig weight gain at weaning was more responsive to total yields of milk and milk nutrients than to composition. These data support the hypothesis that source of metabolizable energy (ME) affects milk yield, composition and efficiency at which the sow converts dietary nutrients into milk.

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Section: Discussionmentioning

confidence: 99%

Yield and Composition of Milk and Weight Gain of Nursing Pigs from Sows Fed Diets Containing Fructose or Dextrose

White¹,

Head²,

Bachman³

et al. 1984

Journal of Animal Science

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“…For instance, rats given a high sucrose diet gained weight more rapidly than those given an isoenergetic glucose diet [1] while rats given a diet containing fructose gained less weight than those containing either glucose or su crose [2], It has been shown that the rate of weight loss of rats on a diet containing glu cose was significantly greater than on an isoenergetic diet containing sucrose [3]. Su crose given to baboons resulted in a greater weight of abdominal fat [4] and greater over all body weight gain [5] when compared to a partial hydrolysate of starch.…”

Section: Introductionmentioning

confidence: 99%

Different Effects of Various Carbohydrates on the Metabolic Rate in Rats

Sharief

Macdonald

1982

Ann Nutr Metab

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Fasting adult male rats were given, by orogastric tube, sucrose, glucose, glucose with fructose and water, and the metabolic rate for the ensuing 150–180 min was measured. It was found that there was an increase in metabolic rate after all sugars, greatest after sucrose and least with glucose and with fructose. With the glucose:fructose mixture the metabolic rate was greater than glucose and less than an equimolar load of sucrose. The respiratory quotient after glucose was less than that after fructose, whereas with sucrose it was greater than an equimolar mixture of glucose and fructose.

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Effect of a High Sugar Intake on Some Metabolic and Regulatory Indicators in Young man

Rath

Masek

Kujalová

et al. 1974

Nahrung

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In six young hospitalized men the effect of a high dietary sugar intake (mean sugar content was 52.5 kcal% on a 2850 kcal-diet) on body-weight, body fat ratio (calculated from body density) and some metabolic and regulatory indicators was investigated. Although there was a great individual variability of values, a statistically significant increase of the body fat was recorded on the zznd day on the high-sugar diet (from k1.0 to 2.1%); a statistically significant increase of cholesterol, triglyceride and esterified fatty acid levels was recorded on the loth day, phospholipids did not change. Two weeks after discontinuation of this diet the investigated indicators practically returned to normal levels. After 24 days on the diet a slight increase of the insulinaemia on fasting was recorded and in four subjects higher maximum values of insulinaemia were obtained after half the amount of glucose. An increased catecholamine excretion was found : of noradrenaline (significant on the 3rd and 10th day on the diet) and of vanilylmandelic acid (significant on the 3rd and 17th day on the diet).Epidemiological investigations revealed a high ratio of sugar in the contemporary diet of man [e.g. I, 21 and demonstrated for instance in the Czech population a rising trend of sugar consumption.Conclusions on the negative effect of a high sugar consumption can be drawn e.g. from the positive association between sugar consumption and the prevalence of ischaemic heart disease (IHD) which was repeatedly demonstrated by YUDKIN [4-6 and others] and which was recorded also under our conditions [3].Many workers studied therefore in more detail the relations between sugar intake and blood lipid levels which are commonly considered indicators of the risk of atherasclerosis: Between the sugar intake and blood lipid levels positive associations were found which suggest relationships between triglyceride and cholesterol levels and sugar consumption [7-111. Other workers studied the mechanisms of this effect. Thus attention was drawn e.g. to the possible participation of insular stimulation in this sucrose-induced hyperlipogenesis [IZ] . For the interpretation of the mechanism of the effect exerted by sugar on the development of IHD the increased adhesiveness 24

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Metabolic Differences between Dietary Liquid Glucose and Sucrose

Cited by 12 publications

References 11 publications

Yield and Composition of Milk and Weight Gain of Nursing Pigs from Sows Fed Diets Containing Fructose or Dextrose

Yield and Composition of Milk and Weight Gain of Nursing Pigs from Sows Fed Diets Containing Fructose or Dextrose

Different Effects of Various Carbohydrates on the Metabolic Rate in Rats

Effect of a High Sugar Intake on Some Metabolic and Regulatory Indicators in Young man

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