Metabolic effects of diet containing blue mussel (Mytilus edulis) and blue mussel-fed salmon in a mouse model of obesity

Azad, Atabak M.; Bernhard, A.; Shen, Anne; Myrmel, Lene Secher; Lundebye, Anne‐Katrine; Lecaudey, Laurène Alicia; Fjære, Even; Ho, Quang Tri; Sveier, Harald; Kristiansen, Karsten; Limborg, Morten T.; Madsen, Lise

doi:10.1016/j.foodres.2023.112927

Cited by 4 publications

References 40 publications

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Are mesopelagic organisms nutritious food? Impact on metabolism, availability of nutrients, and contaminants from dietary intervention in C57BL/6J mice model

Azad,

Myrmel,

Wiech

et al. 2024

Food Frontiers

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Mesopelagic species are unexplored novel low‐trophic sources of essential micronutrients and may contribute to combat malnutrition. In this study, common mesopelagic species from the North Sea including Northern krill (Meganyctiphanes norvegica), glacier lanternfish (Benthosema glaciale), and Muller's pearlside (Maurolicus muelleri) were supplemented in mice feed using a Western diet recipe. The metabolic outcomes were subsequently compared to those of ordinary seafood. Consumption of mesopelagic species induced a large variation in weight gain, in the following order: lanternfish (7.1 g) > krill (14.4 g) > control (19.7 g) > pearlside (22.6 g). The lanternfish‐supplemented diet containing wax esters reduced weight gain and obesity and improved insulin sensitivity. The wax esters from the lanternfish‐supplemented diet were efficiently absorbed, with more than 92% of the fatty alcohols being assimilated. The inclusion of lanternfish and pearlside led to improvements in the fatty acid (FA) composition in the mouse liver, evidenced by increased levels of essential long‐chain polyunsaturated FAs and an increased n‐3/n‐6 ratio (0.7 to 1.45 vs. 0.46 in control group). Notably, no adverse effects were found in mice fed pearlside and lanternfish, although an elevated level of fluoride in femur bone was observed in mice fed a diet supplemented with krill followed by reduced sperm concentration and sperm motility. Collectively, our findings underscore the diverse array of metabolic and physiological effects induced by the consumption of mesopelagic species. Furthermore, these species can be considered as good sources of n‐3 FAs and essential vitamins, suggesting their potential value to human nutrition.

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Are mesopelagic organisms nutritious food? Impact on metabolism, availability of nutrients, and contaminants from dietary intervention in C57BL/6J mice model

Azad,

Myrmel,

Wiech

et al. 2024

Food Frontiers

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Predicting consumers’ intention towards seafood products: An extended theory of planned behavior

Aminizadeh,

Mohammadi,

Karbasi

et al. 2024

Food Quality and Preference

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Farmed blue mussels (Mytilus edulis)—a nutrient-dense resource retaining nutritional value through processing

Bjerknes,

Elvevoll,

Alterskjær Sundset

et al. 2024

Front. Nutr.

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This study investigated how farmed blue mussels (Mytilus edulis) can optimize human nutrient intake. A particular focus was on assessing nutrient preservation during steaming and freeze-drying, processes that could deplete nutrients. The study compared the content of essential amino acids and fatty acids in steamed and freeze-dried blue mussels to the nutritional needs of humans and farmed Atlantic salmon (Salmo salar). Additionally, it assessed the ethyl acetate method versus the traditional, more toxic Folch method for lipid extraction from blue mussels. Both steaming and freeze-drying effectively preserved essential amino acids and fatty acids in blue mussels. A 100 g serving of steamed blue mussels contributes from 26.8 ± 0.78% (Phe) to 54.9 ± 1.66% (Thr) of the daily recommended intake of essential amino acids (EAA). For steamed freeze-dried blue mussels, over 100% of the recommended intake is met for all EAA and as much as 243% for threonine. The 100 g serving will also provide 271 mg eicosapentaenoic acid (EPA; 20:5n-3) and 220 mg docosahexaenoic acid (DHA; 22:6n-3), thus covering the required intake of n-3 long-chain polyunsaturated fatty acids for adults as well as the recommended intake for pregnant and lactating women. Mussels are non-fed filter feeders that generally provide these nutrients with significantly lower environmental footprints, measured as global warming, eutrophication, and acidification, compared to farmed Atlantic salmon. Blue mussels can also be a valuable feed ingredient for farmed Atlantic salmon. Finally, it was demonstrated that the ethyl acetate method is not suited for lipid extraction from blue mussels, as the lipid yield was only half compared to the lipid yield using the Folch method.

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Metabolic effects of diet containing blue mussel (Mytilus edulis) and blue mussel-fed salmon in a mouse model of obesity

Cited by 4 publications

References 40 publications

Are mesopelagic organisms nutritious food? Impact on metabolism, availability of nutrients, and contaminants from dietary intervention in C57BL/6J mice model

Are mesopelagic organisms nutritious food? Impact on metabolism, availability of nutrients, and contaminants from dietary intervention in C57BL/6J mice model

Predicting consumers’ intention towards seafood products: An extended theory of planned behavior

Farmed blue mussels (Mytilus edulis)—a nutrient-dense resource retaining nutritional value through processing

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