Metabolic effects of green tea and of phases of weight loss

The Effect of Dietary Supplementation of Green Tea Catechins on Cardiovascular Disease Risk Markers in Humans: A Systematic Review of Clinical Trials

“…It was beyond the scope of this review to include and examine sources from 'grey' literature. Despite the variability of effect, with some studies finding conflicting outcomes [28][29][30], the majority of the current literature appears to support the positive therapeutic effect derived from GT consumption [1,[9][10][11][12][13][14][15][31][32][33][34]. Furthermore, as tea consumption is high globally, it could be proposed that even modest health effects in humans may have major beneficial implications for global population health and reduction in CVD risk [21,35].…”

“…Of which, 30 were excluded on the basis of: study design (n = 16), missing outcome data (n = 14), and absence of placebo group (n = 1). The seven remaining studies [9][10][11][12][13][14][15] met the inclusion criteria (Table 1), with a cumulative total of 466 participants aged from 16 to 65, with an average age of 47.7˘9.2 years (mean˘SD). Five of the chosen studies [9][10][11][12][13][14][15] included participants of both gender, whilst the remaining three [10,11,13] examined the effects of GT extract supplementation in females only.…”

“…The seven remaining studies [9][10][11][12][13][14][15] met the inclusion criteria (Table 1), with a cumulative total of 466 participants aged from 16 to 65, with an average age of 47.7˘9.2 years (mean˘SD). Five of the chosen studies [9][10][11][12][13][14][15] included participants of both gender, whilst the remaining three [10,11,13] examined the effects of GT extract supplementation in females only. Furthermore, five of the chosen studies [9][10][11][12][13] investigated the effect of interventions on obese participants, two examined people with type 2 diabetes [14,15], and one studied healthy individuals ( Table 1).…”

“…Six of the seven studies used opaque capsulated GT extract as a supplement, with an average daily supplement dose being 640 mg/day (range 300-1500 mg/day) [9][10][11][12][13], while another study supplemented participants with a daily beverage containing 582.8 mg GTCs [15]. The median trial length of the included studies was 12 weeks (range 12-16 weeks).…”

“…with a majority of the chosen articles presenting with a low risk of bias for categories of selection, performance, detection, attrition, and reporting methods (Table 2). However, it should be noted that three studies [11,14,15] were determined as being moderately at risk of selection bias. One study [13] showed moderate risk of attrition bias and another study [11] was deemed to have an unclear risk of bias, as attrition rate was not mentioned in the article.…”