Metabolic Effects on Muscular Tissue

Distribution ratios (intracellular/extracelIular concentration) of a-amino isobutyric acid (AIB) and activities of the transaminases of aianine (Ala AT), aspartate (Asp AT), leucine (Leu AT) and glutamate dehydrogenase (GDH) were determined in tissues of freshly caught plaice, Pleuronectes plutessa, deprived of food for three months. Liver, red muscle and white muscle demonstrated increased distribution ratios for AIB, while the ratios decreased in kidney and gill with deprivation. Values of the distribution ratio were below 1.0 only in white muscle, with kidney and liver having the highest absolute values. Transaminase activities generally rose with deprivation in all tissues, although the absolute increases were greatest in liver and for the two enzymes Ala AT and GDH. These data indicate that with food deprivation, the role of the liver in amino acid metabolism is maintained and slightly enhanced, while that of the kidney is reduced. Both muscle types (red and white) showed increased water content implicating protein mobilization which could enhance the availability ofamino acids for liver gluconeogenesis and metabolite sparing in other tissues during conditions ofdepletion.

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Metabolic Effects on Muscular Tissue

Cited by 2 publications

References 305 publications

THE HORMONAL REGULATION OF ACTIVE ELECTROGENIC Na+-K+-TRANSPORT IN SKELETAL MUSCLE

THE HORMONAL REGULATION OF ACTIVE ELECTROGENIC Na+-K+-TRANSPORT IN SKELETAL MUSCLE

Amino acid transport and interconversions in tissues of freshly caught and food‐deprived plaice, Pleuronectes platessa L.

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