Metabolic Features In Patients with Obstructive Sleep Apnea Hypopnea Syndrome

Abstract

Obstructive sleep apnea hypopnea syndrome (OSAHS) is characterized by repeated breathing pauses during sleep, with slee disruption, intermittent hypoxia, and cardiac, metabolic and neuropsychological disturbances. Metabolic syndrome (MS) is an association of cardiovascular risk factors centered on insulin resistance.The study objective is to calculate the prevalence of MS and its components in a large group of OSAHS patients. We evaluated 350 patients addressed to The Military Hospital Iasi between 2016 and 2017 from the clinical, metabolic and polygraphic poins of view. In 235 of the 350 de patients we found OSAHS. Of the 235 patients with OSAHS, 140 (60%) meet the criteria for MS, versus 29% of the group withut OSAHS (OR = 3.608, CI = 2.1787 - 5.975). Patients with OSAHS were older, more obese, more sedentary, sleepier and presented higher cholesterol values both total cholesterol and HDL fraction, higher tryglicerides values, higher blood sugar values and blood pressure values than patients without OSAHS. The prevalence of the MS in OSAHS patients is 60%, similar to what whas reported and higher by 31% than in the non OSAHS group. Certain components and associated conditions are characteristically linked to OSAHS.