“…Metabolic risk factors are more important in our population, and use of aspirin in such a population has not been systematically studied. 7 Lastly, the reduction in incidence of ACS achieved in developed countries by effective preventive strategies, which partly explained the futility of aspirin has not yet percolated to this part of the world. This would mean that NNT figures may be much smaller, if a real-world trial is conducted in India.…”