Metabolic syndrome among overweight and obese adults in Palestinian refugee camps

Damiri, Basma; Abualsoud, Mohammed; Samara, Amjad; Salameh, Sakhaa

doi:10.1186/s13098-018-0337-2

Cited by 25 publications

(42 citation statements)

References 49 publications

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“…Diabetes risk has been shown to increase with the number of metabolic syndrome components [6–8]. The estimated prevalence of metabolic syndrome differs by age, sex, and ethnicity because variations exist in the frequencies of metabolic components [9–12]. Therefore, the risk of diabetes according to the number of metabolic syndrome components could be different by age, sex, and obesity status.…”

Section: Introductionmentioning

confidence: 99%

Age-specific diabetes risk by the number of metabolic syndrome components: a Korean nationwide cohort study

Lee

Han

Kwon

2019

Diabetol Metab Syndr

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BackgroundMetabolic syndrome is associated with an increased risk of diabetes. This study investigated the associations between the number of metabolic syndrome components and diabetes risk by age, sex and BMI.MethodsData for 19,475,643 participants ≥ 20 years old with no history of diabetes were obtained between 2009 and 2012 and were accessed using the South Korean National Health Insurance Service. Metabolic syndrome was defined according to the modified criteria of the National Cholesterol Education Program Adult Treatment Panel III. We assessed the risk of diabetes according to the number of metabolic syndrome components after stratifying the study participants into groups by age (20–39, 46–64, ≥ 65 years), sex, and BMI (below or above 25).ResultsDuring an average of 5.13 years of follow-up, the incidence rates of diabetes increased with the number of metabolic syndrome components. Age and BMI gradually increased with the number of metabolic syndrome components. The multivariable-adjusted hazard ratios (HRs) for incident diabetes were 1.401, 1.862, 2.47, 3.164 and 4.501 for participants with one through five components, respectively, compared with those without metabolic syndrome components. The risk of diabetes was 1.79-, 2.18-, and 3.05-times higher for participants ≥ 65 years; 2.57-, 3.45-, and 5.18-times higher for participants 40–64 years; and 2.55-, 3.89-, and 6.31-times higher for participants 20–39 years of age with three through five components, respectively, compared to those with no components. There was no difference in the risk of diabetes between men and women. The HRs were 5.63 for participants with a BMI ≥ 25 and 3.98 for those with a BMI < 25 among individuals with five components.ConclusionsThe risk of diabetes was more strongly associated with the number of metabolic syndrome components among younger adults. In addition, the risk of diabetes across the number of metabolic syndrome components was greater in participants with a BMI ≥ 25.

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Section: Introductionmentioning

confidence: 99%

Age-specific diabetes risk by the number of metabolic syndrome components: a Korean nationwide cohort study

Lee

Han

Kwon

2019

Diabetol Metab Syndr

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“…These challenges demand that institutions designed to address and prevent malnutrition reevaluate their approaches-from the USA, where the beneficiaries BMJ Nutrition, Prevention & Health of a federal food assistance programme designed to address food insecurity face disproportionately higher rates of overweight and obesity 24 to emergency settings, where some refugee populations face previously inconceivable high rates of overweight and obesity. 25 These examples illustrate that the consideration of the role of food aid and assistance in addressing the double burden is not just important in Ghana but also in many settings around the world.…”

Section: Resultsmentioning

confidence: 99%

Role of food aid and assistance in addressing the double burden of malnutrition in Ghana: a qualitative policy analysis

Torto

Brownell

2020

BMJNPH

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Background and aimsIn many low-income and middle-income countries, the double burden of malnutrition threatens public health and economic progress, urging a re-evaluation of the roles and responsibilities of nutrition actors, both traditional and non-traditional. This study examines the food aid and assistance activities of the United Nations World Food Programme (WFP)—one non-traditional actor in the double burden conversation—and the potential for these activities to reach beyond their traditional mandate on undernutrition to also address overweight and obesity in Ghana.MethodsInformation on WFP activities in Ghana from 2012 up through its planning into 2023 was extracted from 11 WFP planning, operations and evaluation documents. WFP activities were then judged against the WHO’s framework on the determinants of the double burden of malnutrition to determine their potential to address the double burden. Semistructured interviews were also conducted with 17 key informants in the global nutrition landscape to identify challenges that may complicate the role of WFP and other actors in addressing the double burden.ResultsThe analysis demonstrates that WFP activities in Ghana can serve as a platform on which to address the double burden, particularly by targeting the food access, food systems and socioeconomic disadvantage determinants of the double burden. Actors’ uncertainty with what role WFP should play in addressing the double burden, insufficient government attention to malnutrition and poor data on overweight and obesity were identified as potential challenges that complicate addressing the double burden.ConclusionThe findings suggest that integrating WFP as a partner in the effort to address the double burden in Ghana might help amplify progress. To better address the double burden, WFP might prioritise retrofitting existing activities rather than implementing new interventions.

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“…Obese people have higher risk of coronary heart disease than overweight people (61% and 22% respectively) [2]. Compared with overweight subjects, obese people have higher prevalence of metabolic syndrome (MetS) [3], a complex of cardiometabolic factors that doubles the risk for developing cardiovascular diseases (CVD) [4], which represent the first cause of mortality worldwide [5].…”

Section: Introductionmentioning

confidence: 99%

Differential Effects of Agraz (<i>Vaccinium meridionale</i> Swartz) Consumption in Overweight and Obese Women with Metabolic Syndrome

Marín-Echeverri¹,

Piedrahita-Blandón²,

Galvis-Pérez³

et al. 2020

JFNR

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Obesity implies higher cardiovascular risk (CVR) than overweight. Polyphenol-rich fruits have shown to ameliorate CVR factors (CVRF). It is not clear whether differential effects could be observed between obese and overweight people consuming these fruits. Objective: To evaluate the effects of agraz on CVRF in overweight and obese women with metabolic syndrome (MetS). Methods: Overweight (n=22) and obese (n=18) women (25-60 years) with MetS, were included in this crossover, double-blind and placebo-controlled study. They consumed agraz or placebo over 4-weeks separated by a 4-wk washout period. At the end of each period, the following parameters were measured: anthropometrics, blood pressure, serum lipid profile, glucose, insulin, adipokines, apolipoprotein (apo)-A1, high sensitivity C-reactive protein (hs-CRP), serum total antioxidant capacity (TAC), endogenous antioxidant enzymes and oxidative stress (OxS) markers. Results: Compared to placebo, agraz consumption significantly (p<0.05) reduced hs-CRP and urinary 8-hydroxy 2 deoxyguanosine (8-OHdG) levels in overweight and obese women, respectively. In both groups, changes in antioxidant markers were significant (p<0.05) and negatively correlated with changes in CVR factors and OxS markers, respectively. Positive correlations were observed with cardioprotective markers. Conclusions: Agraz consumption had differential effects in overweight and obese women, with better effects on inflammation and OxS markers, respectively. Further studies should consider these differential responses when analyzing the results of an intervention, and eventually adjust to get better outcomes.

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Metabolic syndrome among overweight and obese adults in Palestinian refugee camps

Cited by 25 publications

References 49 publications

Age-specific diabetes risk by the number of metabolic syndrome components: a Korean nationwide cohort study

Age-specific diabetes risk by the number of metabolic syndrome components: a Korean nationwide cohort study

Role of food aid and assistance in addressing the double burden of malnutrition in Ghana: a qualitative policy analysis

Differential Effects of Agraz (<i>Vaccinium meridionale</i> Swartz) Consumption in Overweight and Obese Women with Metabolic Syndrome

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