“…A study in Framingham, Massachusetts concluded that total cholesterol, blood pressure, and LDL cholesterol are predictors for CHD in the middle-aged white population [18]. In addition to the previous predictors, old age, male sex, low HDL-C, diabetes are associated with altered CHD events in patients with low LDL-C, according to MESA (Multi-Ethnic Study of Atherosclerosis) by the American College of Cardiology Foundation [19].…”