Metabolic Syndrome and Health‐related Quality of Life in Obese Individuals Seeking Weight Reduction

Tsai, Adam Gilden; Wadden, Thomas A.; Sarwer, David B.; Berkowitz, Robert I.; Womble, Leslie G.; Hesson, Louise A.; Phelan, Suzanne; Rothman, Rebecca A.

doi:10.1038/oby.2007.8

Cited by 49 publications

(57 citation statements)

References 28 publications

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“…These findings confront the results of most studies, which support the idea that MetS would be significantly associated with worse QOL [5][6][7][8][9][10][11][12][13]15], even though they corroborate the findings of some studies [26,27,40] which did not find significant association between MetS and QOL after adjustments for confounding factors. It is noteworthy that different QOL assessment instruments had been used in those studies.…”

Section: Discussioncontrasting

confidence: 48%

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Association between metabolic syndrome and quality of life

Saboya

Bodanese²,

Zimmermann³

et al. 2016

Sci Med

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Aims: Despite all progress made in understanding and treating metabolic syndrome, the study of its impact on quality of life is still controversial and not well understood. The aim of this study was to test the hypothesis that metabolic syndrome can be associated with a worse quality of life. Methods: A controlled cross-sectional study included individuals with metabolic syndrome, from the sub-analysis of a randomized clinical trial about lifestyle modification and cardiovascular risk factors, as well as individuals with no metabolic syndrome, attended as outpatients in several clinics at a general university hospital in Southern Brazil. Measurements were made in individual interviews and included data collection, laboratory tests, and application of general scales such as Mini-Mental State Examination and Medical Outcomes Study Short Form, General Health Survey (SF-36). Comparisons of quantitative data used the Student's t test, followed by analysis of covariance or multiple linear regression for adjustment, and correlation coefficient. For categorical data, the Chi-square or Fisher's exact test were used. Results: The study included 229 individuals, 118 metabolic syndrome and 111 no metabolic syndrome. In univariate analysis, metabolic syndrome was significantly associated with lower scores in the social functioning (p<0.001) and role emotional (p=0.019) quality of life domains, and with the Mental Component Summary score of the SF-36 (p=0.013). However, after adjustments for confounding factors, especially body mass index, the significance of these associations was lost. The only significant association between metabolic syndrome and quality of life that has remained after the adjustments was with worse QOL in the role emotional domain, but only in men (p=0.049). Conclusions: After adjusting for multiple variables, metabolic syndrome was significantly associated with decreased quality of life scores in men in the role emotional domain.Key woRds: metabolic syndrome X; risk factors; quality of life.RESuMO objetivos: Apesar dos avanços no entendimento e tratamento da síndrome metabólica, o estudo do seu impacto sobre a qualidade de vida é ainda controverso e inconclusivo. O objetivo deste estudo foi testar a hipótese de que a síndrome metabólica estaria associada à piora da qualidade de vida. Métodos: Um estudo transversal controlado incluiu indivíduos com síndrome metabólica, advindos da subanálise de um estudo controlado randomizado sobre modificação de estilo de vida e fatores de risco cardiovascular; e indivíduos sem síndrome metabólica, provenientes de diversos ambulatórios de um hospital geral no sul do Brasil. As medidas foram realizadas em entrevistas individuais, que incluíram coleta de dados demográficos, testes laboratoriais e aplicação do Exame do Estado Mental e o Medical Outcome Study Short Form, General Health Survey (SF-36). Para comparações entre dados quantitativos, foram utilizados teste t de Student, análise de covariância ou regressão linear múltipla para os ajustes dos fatores confu...

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Section: Discussioncontrasting

confidence: 48%

“…However, eight of them mentioned significant association only in women [16][17][18][19][20][21][22][23], and three of them were exclusively composed of female samples [21][22][23]. Some studies stated that this association only remained significant when MetS was also associated with depression [26] or higher body mass index (BMI) [27].…”

Section: Introductionmentioning

confidence: 99%

Association between metabolic syndrome and quality of life

Saboya

Bodanese²,

Zimmermann³

et al. 2016

Sci Med

View full text Add to dashboard Cite

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“…Patients with MetS had significant lower scores than the AH subjects in the SF subscale. The SF is defined as the limitations in social activities due to physical or emotional health [20] [25]- [27]. The physical limitation for MetS was discussed earlier.…”

Section: Discussionmentioning

confidence: 99%

“…The physical health subscales include those that measure physical function (PF) (i.e., degree of limitation in performing activities of daily living), physical role (PR) (i.e., limitations in daily activities due to physical health), bodily pain (BP) (i.e., limitations in daily activities due to pain), and general health (GH) (i.e., self evaluation of overall health). The mental health subscales include those that measure vitality (V) (i.e., energy and fatigue), social functioning (SF) (i.e., limitations in social activities due to physical or emotional health), emotional role (ER) (i.e., limitations in usual role activities due to emotional problems), and general mental health (GMH) (i.e., psychological distress and wellbeing) [20] [25]- [27]. For each subscale, scores are ranged from 0 (the worst) to 100 (the best) [20] [27].…”

Section: Introductionmentioning

confidence: 99%

“…The mental health subscales include those that measure vitality (V) (i.e., energy and fatigue), social functioning (SF) (i.e., limitations in social activities due to physical or emotional health), emotional role (ER) (i.e., limitations in usual role activities due to emotional problems), and general mental health (GMH) (i.e., psychological distress and wellbeing) [20] [25]- [27]. For each subscale, scores are ranged from 0 (the worst) to 100 (the best) [20] [27]. Higher score in each subscale and both physical component summary (PCS) and mental component summary (MCS) indicate a better functioning and HRQoL [20] [26] [28].…”

Section: Introductionmentioning

confidence: 99%

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Influence of Metabolic Syndrome versus Musculoskeletal Disorders on Saudi Health-Related Quality of Life

El-Sobkey¹,

Hassan²,

Ewais³

2015

OJTR

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Aim: This work aimed to study the influence of two chronic health conditions, metabolic syndrome (MetS) and musculoskeletal disorders (MSDs), on the health-related quality of life (HRQoL) of Saudis. Method: The Medical Outcomes Study Short Form-36 (SF-36) health status questionnaire was used to measure the HRQoL and compare the mean scores of the questionnaire subscales and physical and mental component summaries (PCS and MCS) of 33 patients with MetS, 18 patients with MSDs, and 30 apparently healthy (AH) subjects. Regression analysis was used to measure the prediction power of the study group, age and gender of the participants in estimating the HRQoL. Results: Results showed that the mean scores of the physical subscales, the PCS, the mental subscales and MCS were arranged in descending order from AH subjects, patients with MetS, to patients with MSDs. The mean scores difference among the 3 study groups were statistically significant with the only exception for the general mental health (GMH) subscale (P = 0.404). The study group and age accounted for 41.8% of the variability of PCS while the study group accounted for 19.6% of the variability in the MCS. The resulted equation to estimate the PCS score was as follows: PCS = 113.18 -12.85 (Group: 0 for AH, 1 for MetS, and 2 for MSDs) -0.67 age. On the other hand the resulted equation to estimate the MCS score was as follows: MCS = 76.203 -10.426 (Group: 0 for AH, 1 for MetS, and 2 for MSDs). Conclusion: Patients with MetS and patients with MSDs had lower HRQoL than AH subjects. All the physical and mental dimensions of HRQoL are negatively influenced with MetS and with MSDs with the only exception for the GMH subscale. The physical and mental burden of MSDs is more dominant. The study group and age can be used to predict the PCS while the study group can be used to predict the MCS.

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Binge Eating and Metabolic Syndrome

Jáuregui‐Lobera

2013

Metabolic Syndrome and Neurological Disorders

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Metabolic Syndrome and Health‐related Quality of Life in Obese Individuals Seeking Weight Reduction

Cited by 49 publications

References 28 publications

Association between metabolic syndrome and quality of life

Association between metabolic syndrome and quality of life

Influence of Metabolic Syndrome versus Musculoskeletal Disorders on Saudi Health-Related Quality of Life

Binge Eating and Metabolic Syndrome

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