Metabolic syndrome and its components in southern Kazakhstan: a cross-sectional study

Sadykova, Assel Dauletbaevna; Shalkharova, Zhanar Sailaubekovna; Шалхарова, Ж Н; Садыкова, К Ж; Madenbay, K; Zhunissova, M B; Nuskabayeva, G. O.; Askarova, Saltanat; Grjibovski, Andrej M.

doi:10.1093/inthealth/ihy027

Cited by 4 publications

(2 citation statements)

References 32 publications

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“…According to the authors of diagnostics and management of MetS in the Republic of Kazakhstan, MetS diagnostics criteria should be the same as the European Standards. Studies in Kazakhstan show that the waist circumference (WC) measurement reflects mostly the degree of insulin resistance in patients [25], [26]. By the International Diabetes Federation (IDF) criteria [27] and experts of the Russian Scientific Society of Cardiology on the diagnosis and treatment of MetS [4], MetS was defined as the combination of WC ≥ 80 cm in women and ≥94 cm in men with two and more risk factors (triglycerides ≥1.7 mmol/l, high-density lipoprotein (HDL) cholesterol <1.2 in women, HDL cholesterol < 1.0 mmol/l in men, fasting plasma glucose ≥ 5.6 mmol/l, BP ≥ 130/85 mm Hg, or taking antihypertensive medication).…”

Section: Methodsmentioning

confidence: 99%

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Койчубеков¹,

Sorokina²,

Korshukov³

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Morbidity rate of circulatory system diseases (CSD) in Kazakhstan continues to grow and the metabolic syndrome (MetS) contributes significantly to cardiovascular risk development. It was known that MetS altered autonomic nervous system (ANS) by decreasing parasympathetic activity and global heart rate variability (HRV), at the same time, the decrease in sympathetic modulation is unclear. Studies investigated associations between anxiety and MetS disorders are rather controversial. Research findings of the MetS influence on health-related quality of life (HRQoL) were also contradictory. The above-mentioned justifies the necessity of research to clarify and deepen the MetS etiology and pathogenesis, as well as to improve its diagnostics efficiency and treatment. AIM: The research goals were to study psychophysiological status and HRQoL in individuals with MetS living in Central Kazakhstan. MATERIALS AND METHODS: Three hundred MetS patients were examined in Karaganda city clinical hospital. Statistical methods and spectral analysis of HRV, simple visual-motor reaction (SVMR), the Spielberger State-Trait Anxiety Inventory, and the Lüscher color test were used. SF-36 questionnaire was used for HRQoL assessment. RESULTS: General decrease in the activity of both sympathetic and parasympathetic branches of ANS was observed in MetS patients. More than half of the examined MetS patients have had a high level of trait anxiety. Most MetS patients have had a low level of the central nervous system (CNS) functional activity. MetS patients are active both in physical and social spheres. Bodily pain syndrome greatly influences MetS patients’ life quality. The patients evaluate their health level as being low. CONCLUSION: Individuals with MetS living in Central Kazakhstan had decreased activity of ANS, prevalence of inhibition processes in CNS, high level of trait anxiety, and bodily pain syndrome affecting life quality.

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Section: Methodsmentioning

confidence: 99%

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Койчубеков¹,

Sorokina²,

Korshukov³

et al. 2020

Open Access Maced J Med Sci

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“…Currently, more than a billion people in the world suffer from MetS. In developed countries, the prevalence of MetS among young people, according to scientific sources, among this group in the USA among people aged 20 to 39, increased to 48.6% [1], in European countries to 24.3% [2], in the Russian Federation to 26.7% [3] and in the Republic of Kazakhstan was 17.9% for women and 15.3% for men [4].…”

Section: Introductionmentioning

confidence: 99%

https://doi.org/10.32921/2225-9929-2023-2-51-4-

Kuandyk,

Tardzhibayeva,

Shakanov

et al. 2023

JHD

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Purpose of the study: To study the development characteristics of metabolic syndrome and risk factors in civil servants of Astana city.Methods. The study was conducted in Astana with two groups of study, main group and control group. These groups were consist of 475 people working in civil service and people working in other fields of service aged 18 to 63.Results. To conduct the study we selected people with metabolic syndrome in accordance with the criteria of the International Diabetes Federation (IDF 2009), we also reviewed the case with prevalence of metabolic syndrome in people of studied groups. In the main group, the incidence of metabolic syndrome was 10.6% lower than in the control group and it was found that the majority of them were 53.5% men. The differences between metabolic syndrome components compared to the control group, in men: triglycerides, blood glucose level, high arterial blood pressure (p<0.05), and in women: triglycerides, high-density lipoproteins, high arterial blood pressure (p<0.05). It was noticed, that the combination of the metabolic syndrome components in both groups occurs mainly in the form of waist + glucose + triglyceride circumference. In addition, high arterial blood pressure, triglyceride and smoking were identified as the leading risk factors of this pathological condition among the respondents.Conclusions. There is a characteristic tendency of spreading the metabolic syndrome, the course of components and the accompanying situation among civil servants. It is based on risk factors that influenced. In this way, the given study results can be used as a basis for the formation of preventive measures of metabolic syndrome among civil servants.Keywords: metabolic syndrome, civil servants, prevalence characteristics, risk factors

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Analysis and quantification of double-stranded DNA breaks in blood lymphocytes by detection of γ-H2AX foci during a body mass increase

Bazargaliyev,

Kudabayeva,

Zhexenova

et al. 2024

Obesity Medicine

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Metabolic syndrome and its components in southern Kazakhstan: a cross-sectional study

Abstract: The distribution of components of MetS in southern Kazakhstan is different from other parts of the European World Health Organization region and varies across genders.

Cited by 4 publications

References 32 publications

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

https://doi.org/10.32921/2225-9929-2023-2-51-4-

Analysis and quantification of double-stranded DNA breaks in blood lymphocytes by detection of γ-H2AX foci during a body mass increase

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