Metabolic syndrome and its correlates: A cross-sectional study among adults aged 18–49 years in an Urban Area of West Bengal

Dasgupta, Aparajita; Banerjee, Rajarshi; Pan, Tania; Suman, Sweta; Basu, Utsa; Paul, Bobby

doi:10.4103/ijph.ijph_50_19

Cited by 9 publications

(7 citation statements)

References 3 publications

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“…The mean fatty liver index (FLI) in our study was 55.8 ± 32.1. This is comparable to a study by Dasgupta et al which reported a mean FLI of 58.4 ± 33.2 in adult Indian females (11). Another study from Korea found the mean FLI to be 46.1 ± 26.7 (21).…”

Section: Discussionsupporting

confidence: 87%

“…Increasing FLI was signi cantly associated with adverse cardiometabolic pro le including higher BMI, blood pressure, dysglycemia, and dyslipidemia. Similar associations between worsening metabolic parameters and higher FLI scores have been reported earlier (11,22). This demonstrates the utility of FLI as a marker of metabolic dysfunction.…”

Section: Discussionsupporting

confidence: 83%

“…The prevalence of metabolic syndrome in this study was 61% which is higher compared to other studies from India that reported a prevalence ranging from 18% to 46% (11,19,20). The higher prevalence in this study may be due to the hospital-based nature of the sample.…”

Section: Discussioncontrasting

confidence: 75%

“…We also evaluated the association of FLI with individual components of MetS and related comorbidities. Sample Size Calculation: The sample size is calculated based on a previous study by Dasgupta et al that reported a 45% prevalence of metabolic syndrome in adult females in India (11). Using this prevalence, with an absolute precision of 5% and a con dence level of 95%, the minimum required sample size is calculated using the formula:…”

Section: Introductionmentioning

confidence: 99%

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Fatty Liver Index as a Predictor of Metabolic Syndrome in Adult Females in India

Vamja,

Vala

et al. 2024

Preprint

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Background: Metabolic associated fatty liver disease (MAFLD) is considered the hepatic manifestation of metabolic syndrome (MetS). Fatty liver index (FLI) is a validated model to detect MAFLD. This study aimed to evaluate the accuracy of FLI in predicting MetS in adult females in India. Methods: This cross-sectional study included 450 adult females attending a tertiary care hospital in India. Clinical examination, anthropometric measurements, and biochemical tests were conducted. FLI was calculated using the standard formula. Mets were diagnosed using harmonized criteria. Logistic regression analysis was performed to determine predictors. Results: The mean age was 44.2±7.8 years and the prevalence of MetS was 61%. Increasing the FLI category was significantly associated with a worsening metabolic profile. The odds of hypertension, diabetes, MetS, and cardiovascular disease progressively increased with higher FLI levels (p<0.001), denoting a dose-response relationship. FLI demonstrated good diagnostic accuracy for MetS with AUC 0.86 (95% CI 0.81–0.89). It showed significantly higher predictive ability compared to individual components like waist circumference and lipids. A FLI cutoff ≥30 provided an optimal balance of sensitivity (71%) and specificity (59%) for predicting MetS. Conclusion: FLI demonstrates a strong association with MetS and related comorbidities in a dose-dependent manner. It shows good diagnostic accuracy for predicting MetS, better than individual criteria. FLI can be a simple, low-cost screening tool to identify high metabolic risk individuals in resource-limited settings.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionsupporting

confidence: 83%

Section: Discussioncontrasting

confidence: 75%

Section: Introductionmentioning

confidence: 99%

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Fatty Liver Index as a Predictor of Metabolic Syndrome in Adult Females in India

Vamja,

Vala

et al. 2024

Preprint

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“…Метаболический синдром (МС), характеризованная Всемирной организацией здравоохранения как неинфекционная пандемия ХХI века продолжает оставаться одним из актуальных проблем современной медицины [1,3,10]. Это прежде всего обусловлено высокой частотой его распространенности и прогрессирующим ежегодным ростом почти во всех странах мира [5][6][7]10]. Как показывают ре-зультаты множества проведенных исследований МС и различные его компоненты имеет место у 3,6-26,9% общей популяции и чаще всего распространена среди населения развитых и развивающихся стран [3][4][5][6][7][10][11][12][13][14][15].…”

Section: удкunclassified

Prevalence of metabolic syndrome in Tajikistan

Gulov,

Abdullozoda,

Usmanova

et al. 2023

jour

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Objective. To study the prevalence of metabolic syndrome among the adult population of Tajikistan in the example of pilot districts.Material and methods. A total of 1304 individuals (718 women, 586 men, average age 41.1±13.6 years) from Dushanbe city and the pilot districts of Rudaki and Gissar were screened for metabolic syndrome without prior randomization. The diagnosis was based on clinical and laboratory indicators according to WHO (1999) and IDF (2005) criteria. All participants provided voluntary written consent to partake in the screening.Results and discussion. Using the WHO criteria, metabolic syndrome was identified in 94 (7.2%) people 38 (6.5%) men and 56 (7.8%) women. Hyperglycemia was detected in 97 (7.4%) respondents with a median fasting glucose level of 7.0 (6.8; 8.3) mmol/L. Increased waist to hip circumference ratio (n=174; 13.3%) was observed twice as often in women (n=117; 16.3%) compared to men (n=57; 9.7%) (p<0.001).Dyslipidemia in the form of increased triglycerides (n=372; 28.5%) or decreased high-density lipoproteins (HDL) (n=77; 5.9%) from reference values was identified in one in four participants.Arterial hypertension of varying severity was present in 20 (1.5%) respondents, with no significant difference between men (n=9; 1.54%) and women (n=11; 1.53%) (p>0.05). The median CAD and MAP in this group of respondents was 140.0 (130.0; 145.0) / 95.0 (90.0; 110.0) mmHg, with no discernible gender disparity.Based on the IDF (2005) criteria, metabolic syndrome was identified in 176 (13.5%) participants: 71 (12.1%) men and 105 (14.6%) women. As participant age increased, there was a corresponding rise in the occurrence of metabolic syndrome. Thus, among 18-44-year-old respondents (n=820), 39 (4.8%) had metabolic syndrome, among 45-59 year old (n=328) 36 (10.9%), among 60-74 year old (n=150) 17 (11.3%) and among 75-90 year old (n=6) 2 (33.3%).Conclusion. Metabolic syndrome is detected in 7.2-13.5% of the adult population. Young men and middleaged to elderly women are the most affected demographics. Due to the high prevalence of metabolic syndrome, it is necessary to strengthen organizational measures for its broad prevention among the general population by promoting a healthy lifestyle, healthy diet, and increasing physical activity.

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Association between behavioural risk factors and metabolic syndrome among adult population in India: A systematic review and meta-analysis of observational studies

Krishnamoorthy

Rajaa

Murali

et al. 2022

Nutrition, Metabolism and Cardiovascular Diseases

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Metabolic syndrome and its correlates: A cross-sectional study among adults aged 18–49 years in an Urban Area of West Bengal

Cited by 9 publications

References 3 publications

Fatty Liver Index as a Predictor of Metabolic Syndrome in Adult Females in India

Fatty Liver Index as a Predictor of Metabolic Syndrome in Adult Females in India

Prevalence of metabolic syndrome in Tajikistan

Association between behavioural risk factors and metabolic syndrome among adult population in India: A systematic review and meta-analysis of observational studies

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