Metabolic syndrome components in obese Egyptian children

Zaki, Moushira Erfan; Mohamed, S. M.; Bahgat, Karima A.; Kholoussi, Shams

doi:10.5144/0256-4947.2012.603

Cited by 18 publications

(11 citation statements)

References 35 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study the prevalence of MS in obese children was 36.2% which is higher than the Chinese, 24 Egyptian 25 and Turkish children, 13 but less than three other studies from Iran 26 , 27 and Turkey. 28 …”

Section: Discussioncontrasting

confidence: 72%

Prevalence of Metabolic Syndrome in Elementary School Children in East of Iran

Zardast¹,

Namakin²,

Chahkandi³

et al. 2015

J Cardiovasc Thorac Res

View full text Add to dashboard Cite

Introduction: Metabolic Syndrome (MS) in children and adolescents is becoming a global public health concern. MS tracks into adulthood increasing the risk for type 2 diabetes mellitus and cardiovascular diseases. This study was designed to verify the rate of MS in elementary school students of Birjand, as a representative sample of Iranian children to verify the best preventive measures in this age group. Methods: This descriptive-analytical, cross-sectional study was performed on 1425 elementary school children through multiple-cluster sampling in 2013. Height, weight, waist circumference and blood pressure of children were measured by standard methods. Blood glucose, triglycerides, cholesterol, High-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) levels were also measured after 12 hours fasting. MS was defined according to the Adult Treatment Panel III (ATP-III) based on the National Cholesterol Education Program. Data were analyzed by SPSS using t test and chi-square test. Significance level was set at P < 0.05. Results: The prevalence of MS was 5.3% which increased with age. 43.5% of the studied cases had one or more components of the MS. The most common components were hypertension, abdominal obesity, hypertriglyceridemia, low HDL-cholesterol and impaired fasting glucose, respectively. MS prevalence was 0.9% in normal weight, 11.3% in overweight and 36.2% in obese children. Conclusion: Regarding the high prevalence of MS in elementary school children in our region, screening for obesity is recommended to prevent adulthood complications. Therapeutic lifestyle changes and maintenance of regular physical activity are the most important strategies for preventing childhood obesity.

show abstract

Section: Discussioncontrasting

confidence: 72%

Prevalence of Metabolic Syndrome in Elementary School Children in East of Iran

Zardast¹,

Namakin²,

Chahkandi³

et al. 2015

J Cardiovasc Thorac Res

View full text Add to dashboard Cite

show abstract

“…49,51 The prevalence of MetS among obese children was reported to be more serious than that among normal weight children. 52 Metabolic syndrome was more common in Iranian obese children with a prevalence of 0.9% in normalweighed students, 11.3% in the overweight and 36.2% in the obese group, 53 which is higher than those reported in Chinese, 54 Egyptian, 55 and Turkish children 49 but less than another study from Turkey. 40 Moreover, the prevalence of MetS in overweight/obese French children aged 10-16 years old was 8.9%, 56 and that of Mexican children aged 6-12 years was 6.7%.…”

Section: Discussionmentioning

confidence: 74%

<p>Metabolic Syndrome and Prediabetes Among Yemeni School-Aged Children</p>

Saeed¹,

Al‐Habori²,

Saif-Ali³

et al. 2020

DMSO

View full text Add to dashboard Cite

In view of the high rate of obesity and physical inactivity as well as the rising incidence of Type 2 DM among children in the neighboring Gulf countries and Middle East region; the aim of this study was, therefore, to determine the prevalence of metabolic syndrome (MetS) and prediabetes in Yemeni school-aged children. Patients and Methods: In this study, 1402 school children aged 12-13 years old (grade 7) were recruited from public schools in the capital Sana'a during the period April-May 2013. Anthropometric measurements and BP were recorded and BMI was calculated. Fasting venous blood (5 mL) was collected for biochemical analysis including FBG, HbA1c, insulin and lipids profile. Insulin resistance (HOMA-IR) and β-cell function (HOMA-β) were calculated. Results: The prevalence of prediabetes (as defined by impaired fasting glucose) and MetS (as classified by the IDF 2007) were 0.86% and 0.5%, respectively. Our results also showed 5.21% and 20.26% of the children to have two or one factor(s) of the MetS criteria fulfilled, respectively, with low HDL-c (17%) being the most prevalent MetS component, followed by metabolic glucose (8%), raised TG (5.3%), DBP (1.4%), and high WC (0.5%). Moreover, the prevalence of overweight and obesity was 4.2% and 2.8%, respectively; and about 1.2% of children had abnormal high insulin levels. Children with impaired fasting glucose (IFG) had increased HOMA-IR (p = 0.016) and SBP (p = 0.042) and decreased HDL-c (p = 0.034) and HOMA-β (p < 0.001); whereas obese children had increased WC (p < 0.001) and TG (p = 0.049). Conclusion: The main finding of this study is that Yemeni children are at potential risk of obesity, metabolic syndrome and prediabetes despite their low prevalences. These results highlight the need for early identification and close monitoring of children at risk of later Type 2 DM as an important primary care strategy that can effectively prevent or delay the onset of such condition.

show abstract

“…Obesity is one of the most serious risk factors for chronic diseases. It plays a central role in insulin resistance and metabolic syndrome [ 13 ]. Obese children in our study showed significant elevated serum insulin and insulin resistance (HOMA/IR) than controls.…”

Section: Discussionmentioning

confidence: 99%

Adipokines Vaspin and Visfatin in Obese Children

Salama

Galal

Motawie

et al. 2015

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND:Adipokines provides new insights about the physiology, pathology and treatment of obesity.AIM:We investigated the association between serum vaspin and serum visfatin concentrations with obesity in Egyptian children.MATERIAL AND METHODS:Twenty two obese children with body mass index (BMI) above 95th percentile; 11 males and 11 females were included in this study. Their mean age was 9.18 ± 2.8 years. After general clinical examination, fasting blood glucose, triglycerides, total cholesterol and high density lipoprotein cholesterol were measured in cases and controls (n=11). Fasting insulin, vaspin and visfatin were detected using ELIZA. Insulin resistance was estimated by Homeostasis model assessment method (HOMA-IR).RESULTS:Blood pressure, in both systolic and diastolic measurements was elevated significantly in obese children. Significant elevation of serum insulin and insulin resistance (HOMA/IR) were observed in obese children too. Vaspin and visfatin showed significant elevation in obese children than controls. Significant positive correlations were detected between visfatin and BMI, waist circumference, hip circumference and HOMA/IR. We found that Vaspin and visfatin are higher in obese children.CONCLUSION:Visfatin but not vaspin correlates positively with waist circumference and HOMA/IR in obese children.

show abstract

Metabolic syndrome components in obese Egyptian children

Cited by 18 publications

References 35 publications

Prevalence of Metabolic Syndrome in Elementary School Children in East of Iran

Prevalence of Metabolic Syndrome in Elementary School Children in East of Iran

<p>Metabolic Syndrome and Prediabetes Among Yemeni School-Aged Children</p>

Adipokines Vaspin and Visfatin in Obese Children

Contact Info

Product

Resources

About