Metabolic syndrome in Japanese diagnosed with visceral fat measurement by computed tomography

Early gastric cancer shows different associations with adipose tissue volume depending on histological type

“…In female patients, TFA and VFA in the older group were signifi cantly larger than those in the younger group. The same trend was reported for BMI in the general Japanese population [64]. These data indicate that adipose tissue volume and distribution are not markedly changed by the presence of early cancer lesions in the stomach.…”

Visceral Obesity in Japanese Patients with Metabolic Syndrome: Reappraisal of Diagnostic Criteria by CT Scan

“…However, it has not been confirmed that the relationship between the level of VFA and the number of associated obesity-related diseases is quantitatively the same in both genders. Actually, a gender difference in the association of visceral fat accumulation with the other components of metabolic syndrome was recently reported by Miyawaki et al (13) and was confirmed in the present study as well (Fig. 5).…”

“…5). Miyawaki et al (13) analyzed data from 3,574 Japanese subjects aged 40-59 years obtained during health examinations. The sensitivity and the specificity of VFA cutoff to predict metabolic syndrome were 0.72 and 0.55 at 95 cm 2 and 0.67 and 0.60 at 100 cm 2 in males, and the values in females were 0.73 and 0.70 at 65 cm 2 and 0.66 and 0.74 at 70 cm 2 .…”

“…3), the ACM cutoff levels for males and females were calculated in the present study to be 83 cm and 78 cm, respectively. Miyawaki et al (13) calculated ACM cutoff levels for males and females of 86 cm and 77 cm, respectively, based on their VFA cutoff levels of 100 cm 2 in males and 65 cm 2 in females. Although VFA was not determined in their study, Hara et al (14) recently applied the waist circumference data for 692 subjects (age: 30-80 years) who had undergone annual health examinations to ROC analysis to determine the ACM cutoff for diagnosis of metabolic syndrome.…”

Rationale and design of the KYOTO HEART study: effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high risk of cardiovascular events

“…These differences may be partly explained by differences in the lifestyle of Japanese and Western populations, which are reflected in body mass index (mean BMI: 23-25 and 28-30 kg/m 2 , respectively). 6,7 Most of mortality-morbidity trials have been carried out in Western country, in which none or only a minority of East Asian patients were included. Owing to the paucity of large-scale trials in East Asian people, it remains to be determined whether the results from similar clinical trials in Western societies are internationally applicable to East Asian races or the Japanese population, or whether genetic background can cause different pharmacokinetic and pharmacodynamic responses to the same drug.…”