Metabolic Syndrome in Patients With Abdominal Obesity

Abstract

Background The metabolic syndrome is a constellation of risk factors of metabolic origin that are accompanied by increased risk for cardiovascular disease and type 2 diabetes. The two major underlying risk factors for the metabolic syndrome are obesity and insulin resistance. The aim of this study is to study obesity prole, lipid prole, hsCRP, GGTand microalbuminuria in patients with metabolic syndrome and compare with that of healthy controls. Materials and methods Total 100 subjects were taken for the study. 50 were patients of metabolic syndrome and 50 were healthy controls. Patients were examined for the features of metabolic syndrome and complications of obesity, between May 2012 – June 2013. All patients were evaluated by history, clinical examination and relevant investigations. Results Waist circumference, WHR and BMI were proportionately high in patients with metabolic syndrome when compared to healthy controls. Signicant increase in lipid parameters, fasting blood glucose, hsCRP, GGT and microalbuminuria were seen in patients with metabolic syndrome as compared to healthy controls. Conclusion Our study support the growing evidence that waist circumference can serve as a practical screening method for the metabolic risks that often accompany overweight and obesity. The message emerging from this study is how best to dene and screen for metabolic syndrome, considering energy stores on the one hand and health risks on the other.