Metabolic syndrome in untreated patients with psoriasis: case‐control study

Abstract

reported in psoriatic patients. Total sperm count, sperm mo-tility and percent of spermatozoa with normal morphology were significantly reduced in patients compared to controls. suPAR levels were significantly increased in patients compared to controls and found to be above the reference limits. Ultrasound signs of inflammation of the accessory glands were observed in 35/50 patients with psoriasis and in none of the controls. Conclusion: Our study suggests that untreated psoriasis may impair male fertility. We also found that this might be due to an impact of systemic inflammation on the hormonal profile and on sexual accessory gland inflammation .

Myocardial scintigraphy – a method for detecting cardiac comorbidity in psoriasis patients?

“…Damevska et al. obtained similar figures in their case‐control study . Albeit statistically not significant, our study revealed a higher body weight, BMI, and obesity rate in patients with pathological myocardial scintigraphy.…”

Prevalence of metabolic syndrome in children with moderate to severe psoriasis treated with TNF inhibitors in comparison to conventional agents

“…Triglyceridemia was significantly more prevalent in Group B [143/236(60.59%) patients], than in Group A (51.27%). Similarly, hypertriglyceridemia and abdominal obesity were strongly associated with psoriasis in the Damevska et al () study. Although the HDL cholesterol levels were found to be reduced in our patients.…”

“…A Danish research investigating the Danish National Patient Register for the period 1977–2001 identified a total of 1,074 (0.36%) of the schoolchildren with psoriasis. Multivariate analysis demonstrated an association between excess increase in body mass index and psoriasis in females only (Damevska, Neloska, Gocev, & Mihova, ). Wherein, the females showed a significant association between psoriasis and body mass index at ages 12 ( p = .028) and 13 years ( p = .010).…”

Complementary and integrative therapies for psoriasis: Looking forward

“…Aside from the burden of psoriatic arthritis, some studies suggest that people with psoriasis, particularly those with severe disease, may be at increased risk of cardiovascular disorders. Associations with other co‐morbidities such as metabolic syndrome, chronic obstructive pulmonary disease, liver disease, renal failure, lymphoma and non‐melanoma skin cancer, and rheumatoid arthritis, have also emerged (Damevska, Neloska, Gocev, & Mihova, ; Gottlieb, Chao, & Dann, ).…”