Metabolic syndrome: regulation of metabolism in men (literature review)

Abstract

The review of modern literature on pathogenetic ways of formation of metabolic syndrome in men of different age groups, athletes, University students, as well as persons related to dangerous professions (military personnel, rescuers, liquidators of the consequences of the Chernobyl accident) is presented. The role of insulin resistance, leptin resistance, chronic sluggish inflammation, desynchronosis, and obesity is discussed. Literature data on the relationship of the gut microbiota and vitamin D levels with obesity are presented. The analysis of patent research in the field of clinical and laboratory diagnostics of metabolic syndrome. The role of stress in the development of metabolic syndrome in dangerous professions is shown. Analysis of data published in the literature suggests that hyperleptinemia and low androgen levels can be considered as an additional laboratory marker of MS in liquidators of the Chernobyl accident.