Metabolism and fate of diflubenzuron in swine

Opdycke, Joseph C.; Miller, Richard W.; Menzer, Robert E.

doi:10.1021/jf00114a055

Cited by 12 publications

(10 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In pigs, after oral administration, 82% of the dose was recovered in the feces as unchanged diflubenzuron, and 5% in the urine in the form of various metabolites. Residues in tissues were rather low (<0.5 mg/kg), particularly in subcutaneous fat (0.2 mg/kg) and blood (0.06 mg/kg) [224].…”

Section: Fate Of Bpus In Treated Domestic Animals and Fishmentioning

confidence: 99%

Benzoylphenyl ureas as veterinary antiparasitics. An overview and outlook with emphasis on efficacy, usage and resistance

Junquera¹,

Hosking²,

Gameiro³

et al. 2019

Parasite

View full text Add to dashboard Cite

Six benzoylphenyl ureas are currently used in formulations approved as veterinary medicines: diflubenzuron for fly control mainly on cattle, lice and blowfly strike control on sheep, and lice control on farmed salmonids; lufenuron for flea control on dogs and cats and for lice control on farmed salmonids; triflumuron for lice and blowfly strike control on sheep; fluazuron for tick control on cattle; teflubenzuron for lice control on farmed salmon; and novaluron for fly and tick control on cattle and for flea control on dogs. Resistance to diflubenzuron and triflumuron has already been reported for sheep body lice and blowflies, and to fluazuron in cattle ticks. These and other minor veterinary usages, as well as the current status of resistance, are reviewed and perspectives for future opportunities are discussed based on unexplored potentials and threats posed by future resistance development.

show abstract

Section: Fate Of Bpus In Treated Domestic Animals and Fishmentioning

confidence: 99%

Benzoylphenyl ureas as veterinary antiparasitics. An overview and outlook with emphasis on efficacy, usage and resistance

Junquera¹,

Hosking²,

Gameiro³

et al. 2019

Parasite

View full text Add to dashboard Cite

show abstract

“…Radioassay Techniques. Radiolabeled materials were detected with a Packard TriCarb liquid scintillation spectrometer (Model 3375) using toluene-based, organic, and aqueous scintillators as described by Opdycke et al, 1982. [14C]-n-Hexadecane (Radiochemical Centre, Amersham, England) was used for internal standardization of counting efficiency. Radioactivity was detected on thin-layer chromatograms using both the Varían Aerograph Series 6000 thin-layer scanner equipped with a dual rate meter integrator (Berthold LB 242K) and Kodak No-Screen medical X-ray film to which the plates were exposed for 3-15 days.…”

Section: Metabolism Of Trifluralin In Ratsmentioning

confidence: 99%

Metabolism of trifluralin in rats

Erkog¹,

Menzer²

1985

J. Agric. Food Chem.

Self Cite

View full text Add to dashboard Cite

“…MATERIALS AND METHODS Chemicals. [14C]Diflubenzuron, uniformly radiolabeled in both rings (specific activity 17.42 thesized in this laboratory as previously described (Opdycke et al, 1982). Sodium phenobarbital and glucosee-phosphate dehydrogenase were obtained from Sigma Biochemicals, and SKF-525A was obtained from Smith Kline & French.…”

mentioning

confidence: 99%

“…Sodium phenobarbital and glucosee-phosphate dehydrogenase were obtained from Sigma Biochemicals, and SKF-525A was obtained from Smith Kline & French. Radioassay techniques used were also previously described (Opdycke et al, 1982).…”

mentioning

confidence: 99%