Metabolism of glycerol in pigs fed diets containing mixed crude glycerin and β-adrenergic agonist

Abstract

The optimised use of mixed crude glycerin (MCG) and ractopamine hydrochloride (RH) in diets for finishing pigs requires a better understanding of glycerol metabolism. Therefore, the present study evaluated the performance, blood parameters, metabolite concentrations in the Longissimus lumborum muscle and the activity of enzymes in the liver, subcutaneous adipose tissue and kidney of pigs fed diets containing MCG and/or RH. According to the initial weight, 64 barrows were distributed in a 4 × 2 factorial design, corresponding to four concentrations of MCG (0, 100, 150, and 200 g/kg) in diets containing 0 or 10 mg/kg of RH. There was no MCG × RH interaction for any of the evaluated parameters (P > 0.05). Moreover, there was no isolated effect of dietary MCG or RH on the weight gain and the blood concentrations of glucose, insulin, triacylglycerols, total cholesterol, total protein, albumin, creatinine, cortisol and lactate (P > 0.05). There was a higher rate of phosphorylation of glycerol in the liver, stimulation of lipogenesis in adipose tissue and a likely increase in the utilisation of glycerol by muscle fibres in response to an increased concentration of circulating glycerol from the diet (P < 0.05). In contrast, when the diet contained up to 200 g/kg MCG and 10 mg/kg RH, there were indications of a lower utilisation of glycerol for the synthesis of triacylglycerols in muscle, liver and adipose tissue, in addition to increased oxidation of amino acids in the liver followed by improved feed conversion of pigs (P < 0.05).

Effect of glycerol as an energy source with or without probiotic on carcass trait, litter moisture per cent, haematological and serum metabolites in broiler chicken

“…Present study data is consistent with Mousa et al (2018) who observed that crude glycerol supplementation in the broilers did not show any significant effect on serum total protein, albumin, globulin, serum glucose and HDL level. Pinto et al (2019) who reported that blood glucose, total protein, albumin did not differ significantly among the treatment groups in the pigs fed diet containing mixed crude glycerine and ractopamine hydrochloride. Serum protein and uric acid concentration remain quiet similar between the groups (Erol et al 2009) The litter moisture (%) of various treatment groups fed with glycerol with or without probiotic is shown Table 4.…”

“…Haematological and blood biochemical profile of experimental broiler chickens fed glycerol with or without probiotic by glycerol supplementation Pinto et al (2019). reported that serum cholesterol level did not affected by supplementation of glycerol.Mousa et al (2018) reported that LDL level was significantly reduced in birds fed diet with 5% crude glycerol compared to broilers fed standard diet which recorded highest value.…”