Metabolism of selenium in a selenium-dependent bacterium

Razak, A. A.; Ramadan, Shadia E.; el-Zawahry, K

doi:10.1007/bf02990413

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Fifteen pathways were attributed to the skin microbiota of Atlantic salmon in seawater after 4 weeks. This finding indicates that the SW.4W group has bacteria that can synthesise and/or scavenge lipoate 37 and metabolise selenite into selenomethionine, selenocysteine/selenocystine, and selenocystathionine 38 . The bacterial community can use sulfate/thiosulfate/sulfonates/methionine/cysteine-derived compounds (glutathione) as sulfur sources, use serine to synthesise cysteine, or take up cysteine directly from the environment via ABC transporters or symporters 39 .…”

Section: Discussionmentioning

confidence: 88%

Transition from freshwater to seawater reshapes the skin-associated microbiota of Atlantic salmon

Lokesh

Kiron

2016

Sci Rep

166

132

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Knowledge concerning shifts in microbiota is important in order to elucidate the perturbations in the mucosal barrier during the transitional life stages of the host. In the present study, a 16S rRNA gene sequencing technique was employed to examine the compositional changes and presumptive functions of the skin-associated bacterial communities of Atlantic salmon reared under controlled laboratory conditions and transferred from freshwater to seawater. Proteobacteria was the dominant phylum in salmon from both freshwater (45%) and seawater (above 89%). Bacteroidetes, Actinobacteria, Firmicutes, Cyanobacteria and Verrucomicrobia were the most abundant phyla in salmon from freshwater. The transition to seawater influenced the OTU richness and evenness. The high abundance (~62%) of the genus Oleispira made Proteobacteria the most significantly abundant phylum in salmon from seawater. The predictive functional profile suggested that the communities had the ability to extract energy from amino acids in order to maintain their metabolism and scavenge and biosynthesise compounds to make structural changes and carry out signalling for their survival. These findings need to be further explored in relation to metabolic processes, the fish genotype, and the environment.

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Section: Discussionmentioning

confidence: 88%

Transition from freshwater to seawater reshapes the skin-associated microbiota of Atlantic salmon

Lokesh

Kiron

2016

Sci Rep

166

132

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“…The role of selenoamino acids in Francisella pathogenesis is currently unaddressed but may reflect the facultative intracellular lifestyle of this bacterium. Selenoamino acids were found to be important for the metabolism of other bacteria (41,42). Several key genes in selenocompound metabolism are found in LVS (KEGG pathway ftl00450).…”

Section: Pathway Activation Analysis Implicates Macropinocytosis As Amentioning

confidence: 99%

Temporal Transcriptional Response during Infection of Type II Alveolar Epithelial Cells with Francisella tularensis Live Vaccine Strain (LVS) Supports a General Host Suppression and Bacterial Uptake by Macropinocytosis

Bradburne

Verhoeven

Manyam

et al. 2013

Journal of Biological Chemistry

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Background:The mechanism of Francisella LVS entry into A549 cells is unknown. Results: Microarrays were performed at early infection time points, supported by phenotypic observations and inhibition experiments. Conclusion: Francisella LVS may enter A549 cells by macropinocytosis and quiets the host infection response. Significance: Francisella LVS induces significant host cell signaling at very early time points after the bacteria's interaction with the cell.

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“…Besides, several bacterial strains have been shown to transform selenite into the diselenide amino acid selenocystine R-Se-Se-R [21][22][23]. The R-Se-Se-R species could be due to a reduction of the internalized selenite species.…”

Section: Selenate Exposurementioning

confidence: 99%

Resistance, accumulation and transformation of selenium by the cyanobacterium Synechocystis sp. PCC 6803 after exposure to inorganic Se^VI or Se^IV

Gouget¹,

Avoscan²,

Sarret³

et al. 2005

Radiochimica Acta

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Our purpose was to investigate the ability of Synechocystis sp. PCC 6803, a photosynthetic prokaryote isolated from fresh water, to resist, incorporate and reduce the oxidized forms of selenium including selenite and selenate, the major selenium species present in aquatic systems. Selenium speciation and the chemical intermediates during selenium transformation were determined by X-ray absorption near edge structure (XANES) spectroscopy. The possible internalisation pathways involving selenium and the metabolic fate of selenate and selenite were examined. Selenate metabolism seemed to proceed via the sulfate reduction pathway resulting in the formation of the R-Se-H, R-Se-R and R-Se-Se-R species. The transformation of selenate to toxic amino acids may explain the high sensitivity of Synechocystis to selenate. Several mechanisms of selenium reduction seem to compete during selenite assimilation. A specific mechanism may transform internalised selenite into selenide and, subsequently induce the biosynthesis of selenoproteins. A non-specific mechanism may interfere with thiols, such as glutathione in the cell cytoplasm, or with proteins in the periplasm of the bacteria, notably thioredoxins. Several hypotheses concerning the complex transformation of selenium in Synechocystis could therefore be proposed.

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Metabolism of selenium in a selenium-dependent bacterium

Cited by 3 publications

References 6 publications

Transition from freshwater to seawater reshapes the skin-associated microbiota of Atlantic salmon

Transition from freshwater to seawater reshapes the skin-associated microbiota of Atlantic salmon

Temporal Transcriptional Response during Infection of Type II Alveolar Epithelial Cells with Francisella tularensis Live Vaccine Strain (LVS) Supports a General Host Suppression and Bacterial Uptake by Macropinocytosis

Resistance, accumulation and transformation of selenium by the cyanobacterium Synechocystis sp. PCC 6803 after exposure to inorganic Se^VI or Se^IV

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Metabolism of selenium in a selenium-dependent bacterium

Cited by 3 publications

References 6 publications

Transition from freshwater to seawater reshapes the skin-associated microbiota of Atlantic salmon

Transition from freshwater to seawater reshapes the skin-associated microbiota of Atlantic salmon

Temporal Transcriptional Response during Infection of Type II Alveolar Epithelial Cells with Francisella tularensis Live Vaccine Strain (LVS) Supports a General Host Suppression and Bacterial Uptake by Macropinocytosis

Resistance, accumulation and transformation of selenium by the cyanobacterium Synechocystis sp. PCC 6803 after exposure to inorganic SeVI or SeIV

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Resistance, accumulation and transformation of selenium by the cyanobacterium Synechocystis sp. PCC 6803 after exposure to inorganic Se^VI or Se^IV