Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis

Yamamoto, Shinya; Bamba, Takeshi; Sano, Atsushi; Kodama, Yukako; Imamura, Miho; Obata, Akio; Fukusaki, Eiichiro

doi:10.1016/j.jbiosc.2012.03.023

Cited by 49 publications

(22 citation statements)

References 16 publications

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“…R 2 (proportion of explained variance), and Q 2 (proportion of predicted variance) values were used to further evaluate model quality. In general, an R 2 ≥ 0.65 and Q 2 ≥ 0.5 indicate satisfactory quantitative predictive ability[ 38 ]. In our study, R 2 and Q 2 were 0.756 and 0.734, respectively, for which tested gene expression data of embryo-larvae induced by racemic and (+)- PCB149 for PLS.…”

Section: Discussionmentioning

confidence: 99%

Exploration of Stereoselectivity in Embryo-Larvae (Danio rerio) Induced by Chiral PCB149 at the Bioconcentration and Gene Expression Levels

Chai

Cui

et al. 2016

PLoS ONE

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This paper was designed to study stereoselective enrichment and changes in gene expression when zebrafish (Danio rerio) embryo-larvae were exposed to racemic, (-)- or (+)- PCB149 (2,2’,3,4’,5’,6- hexachlorobiphenyl). Based on bioconcentration analysis, non-racemic enrichment was significantly observed after racemic exposure. No isomerization between the two isomers was found after (-)/(+)-PCB149 exposure. Furthermore, based on gene expression-data mining, CYPs genes (cyp2k6, cyp19a1b, and cyp2aa4) were differential genes after (+)-PCB149 exposure. No obvious differences of dysregulation of gene expression caused by racemic and (-)-PCB149, were observed in embryo-larvae. The above results suggested that (-)-PCB149 could be considered as the main factor causing the dysregulation of gene expression in embryo-larvae after racemic exposure; and (+)-PCB149 should be pursued apart from the racemate, when considering the toxicity of chiral PCB149. Thus, the information in our study could provide new insights to assess the environmental risk of chiral PCBs in aquatic systems.

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Section: Discussionmentioning

confidence: 99%

Exploration of Stereoselectivity in Embryo-Larvae (Danio rerio) Induced by Chiral PCB149 at the Bioconcentration and Gene Expression Levels

Chai

Cui

et al. 2016

PLoS ONE

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“…The quality of each types of soy sauce differs in terms of their components due to different raw material compositions and production method. These are thought to contribute to the different types and compositions of breakdown products that are released during fermentation, which consequently impart the flavor characteristics of soy sauce (Yamamoto et al 2012). Therefore, in this study it is important to comprehend the relationships between the chemical characteristics and sensory attributes of sweet, salty, light and dark type of soy sauces with their production method.…”

Section: Introductionmentioning

confidence: 99%

Chemical Profiling of Different Types of Soy Sauce and the Relationship with its Sensory Attributes

Syifaa

Selamat

Sanny

et al. 2016

Journal of Food Quality

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Four types of soy sauce which are widely consumed and commercially available in Southeast Asia, namely sweet, salty, light and dark soy sauce were discriminated. A comprehensive chemical profiling such as sodium chloride, sugars, organic acids, total nitrogen and free amino acids were determined. The sensory attributes were determined using the Quantitative Descriptive Analysis (QDA) and their relationship with chemical profiles were analyzed by multivariate approach using orthogonal partial least square discriminant analysis (OPLS‐DA). Results showed that sugar was the dominant compound in sweet, salty and dark soy sauce. The sensory attributes such as color, caramel odor, viscosity and sweetness taste increased the overall acceptance in these types of soy sauce. In light soy sauce, sodium chloride, total nitrogen and free amino acids appeared to be dominant compound. It was found that saltiness and umami taste were the important sensory attributes that well‐characterized the taste of light soy sauce. Practical Applications In Southeast Asia, sweet, salty, light and dark types of soy sauce are very popular and commonly used in cooking and as a table condiment. Variations in raw materials used and different production process of different types of soy sauce may contribute to the different chemical profiles and sensory attribute of soy sauce. This aims of this study were to provide general understanding of the chemical characteristics in sweet, salty, light and dark types of soy sauce and highlight the differences between them. In addition, the results of this study can be used to provide additional data for the purpose of standardization and quality improvement of soy sauce production.

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“…e author's group nally discovered that some dipeptides might a ect the di erence of Umai. [25][26][27] ese ndings can be theoretically used for design of soy sauce avor in future. Japanese Sake is produced via complicated process, in which sacchari cation and ethanol fermentation are performed in parallel.…”

Section: Application To Quality Analysis Of Several Foodsmentioning

confidence: 99%

Application of Metabolomics for High Resolution Phenotype Analysis

Fukusaki

2014

Mass Spectrometry

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Metabolome, a total pro le of whole metabolites, is placed on downstream of proteome. Metabolome is thought to be results of implementation of genomic information. In other words, metabolome can be called as high resolution phenotype. e easiest operation of metabolomics is the integration to the upstream ome information including transcriptome and/or proteome. ose trials have been reported at a certain scienti c level. In addition, metabolomics can be operated in stand-alone mode without any other ome information. Among metabolomics tactics, the author's group is particularly focusing on metabolic ngerprinting, in which metabolome information is employed as explanatory variant to evaluate response variant. Metabolic ngerprinting technique is expected not only for analyzing slight di erence depending on genotype difference but also for expressing dynamic variation of living organisms. e author introduces several good examples which he performed. ose are useful for easy understanding of the power of metabolomics. In addition, the author mentions the latest technology for analysis of metabolic dynamism. e author's group developed a facile analytical method for semi-quantitative metabolic dynamism. e author introduces the novel method that uses time dependent variation of isotope distribution based on stable isotope dilution.

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Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis

Cited by 49 publications

References 16 publications

Exploration of Stereoselectivity in Embryo-Larvae (Danio rerio) Induced by Chiral PCB149 at the Bioconcentration and Gene Expression Levels

Exploration of Stereoselectivity in Embryo-Larvae (Danio rerio) Induced by Chiral PCB149 at the Bioconcentration and Gene Expression Levels

Chemical Profiling of Different Types of Soy Sauce and the Relationship with its Sensory Attributes

Application of Metabolomics for High Resolution Phenotype Analysis

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